The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2018

Filed:

Aug. 24, 2016
Applicants:

Ajeet Kaushik, Doral, FL (US);

Madhavan Nair, Coral Gables, FL (US);

Inventors:

Ajeet Kaushik, Doral, FL (US);

Madhavan Nair, Coral Gables, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 33/569 (2006.01); G01N 33/553 (2006.01); G01N 27/327 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5438 (2013.01); G01N 27/3278 (2013.01); G01N 33/553 (2013.01); G01N 33/56983 (2013.01); G01N 2333/185 (2013.01);
Abstract

The subject invention provides materials and methods for detecting Zika virus. Specific embodiments provide an electrochemical immunosensing device and the methods of making and using the same for detecting Zika virus with exceptionally low detection limit. In some embodiments, the immunosensing device is capable of detecting picomolar (pM) level of Zika virus present in a sample by employing immunosensors functionalized with Zika virus binding ligands such as monoclonal Zika virus antibodies and Zika non-structural proteins. In an exemplary embodiment, the immunosensing device can be integrated with microelectronics to be adopted as point-of-care sensing systems. Advantageously, technologies provided herein offer rapid, on-site biosensing methods for the accurate detection of diseases caused by Zika virus.


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