The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2018

Filed:

Aug. 02, 2016
Applicant:

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Manu Prakash, Cambridge, MA (US);

Neil Gershenfeld, Somerville, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 35/08 (2006.01); G01N 1/10 (2006.01); B01L 3/00 (2006.01); G01N 1/20 (2006.01); F16K 99/00 (2006.01); F16L 55/00 (2006.01); G01N 15/06 (2006.01); G01N 1/00 (2006.01);
U.S. Cl.
CPC ...
G01N 1/2035 (2013.01); B01L 3/502746 (2013.01); B01L 3/502784 (2013.01); F16K 99/0001 (2013.01); F16K 99/0019 (2013.01); F16L 55/00 (2013.01); G01N 15/06 (2013.01); B01L 2200/0673 (2013.01); B01L 2300/02 (2013.01); B01L 2400/086 (2013.01); F16K 2099/0084 (2013.01); F16K 2099/0092 (2013.01); G01N 2001/002 (2013.01); Y10T 137/2076 (2015.04); Y10T 137/87153 (2015.04); Y10T 137/87249 (2015.04); Y10T 137/9247 (2015.04); Y10T 436/11 (2015.01); Y10T 436/25 (2015.01); Y10T 436/2575 (2015.01); Y10T 436/25625 (2015.01);
Abstract

Fluid-based no-moving part logic devices are constructed from complex sequences of micro- and nanofluidic channels, on-demand bubble/droplet modulators and generators for programming the devices, and micro- and nanofluidic droplet/bubble memory elements for storage and retrieval of biological or chemical elements. The input sequence of bubbles/droplets encodes information, with the output being another sequence of bubbles/droplets or on-chip chemical synthesis. For performing a set of reactions/tasks or process control, the modulators can be used to program the device by producing a precisely timed sequence of bubbles/droplets, resulting in a cascade of logic operations within the micro- or nanofluidic channel sequence, utilizing the generated droplets/bubbles as a control. The devices are based on the principle of minimum energy interfaces formed between the two fluid phases enclosed inside precise channel geometries. Various devices, including logic gates, non-volatile bistable memory, ring oscillators, bubble synchronizers, analysis chips, sample collectors, and printers have been designed.


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