The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2018

Filed:

Oct. 15, 2012
Applicants:

Steven B. Abramson, Rye, NY (US);

Jose U. Scher, Jersey City, NJ (US);

Dan R. Littman, New York, NY (US);

Eric G. Pamer, Guilford, CT (US);

Inventors:

Steven B. Abramson, Rye, NY (US);

Jose U. Scher, Jersey City, NJ (US);

Dan R. Littman, New York, NY (US);

Eric G. Pamer, Guilford, CT (US);

Carles Ubeda, Valencia, ES;

Randy S. Longman, New York, NY (US);

Andrew Sczesnak, Berkeley, CA (US);

Assignees:

NEW YORK UNIVERSITY, New York, NY (US);

MEMORIAL SLOAN-KETTERING CANCER CENTER, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G01N 33/569 (2006.01); C12Q 1/689 (2018.01); C12Q 1/6883 (2018.01); C12Q 1/18 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/689 (2013.01); C12Q 1/18 (2013.01); C12Q 1/6883 (2013.01); G01N 33/56911 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/102 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01);
Abstract

Methods, reagents and compositions thereof for predicting RA onset in susceptible individuals, diagnosing RA onset, and/or evaluating efficacy of a therapeutic regimen for treating RA are described herein. Determining the amount of a particular bacterial species comprising SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3 (SEQ ID NO: 1+ bacteria) serves as a biomarker for the above indications.


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