The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2018

Filed:

Feb. 02, 2017
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Amjad Ali, Freehold, NJ (US);

Michael Man-Chu Lo, Bedminster, NJ (US);

Yeon-Hee Lim, Piscataway, NJ (US);

Andrew Stamford, Chatham, NJ (US);

Rongze Kuang, Green Brook, NJ (US);

Paul Tempest, Shanghai, CN;

Younong Yu, East Brunswick, NJ (US);

Xianhai Huang, Warren, NJ (US);

Timothy J. Henderson, New Providence, NJ (US);

Jae-Hun Kim, Scotch Plains, NJ (US);

Christopher Boyce, Flemington, NJ (US);

Pauline Ting, New Providence, NJ (US);

Junying Zheng, New Providence, NJ (US);

Edward Metzger, Somerset, NJ (US);

Nicolas Zorn, Durmenach, FR;

Dong Xiao, Warren, NJ (US);

Gioconda V. Gallo, Summit, NJ (US);

Walter Won, San Carlos, CA (US);

Heping Wu, Edison, NJ (US);

Qiaolin Deng, Edison, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A01N 43/46 (2006.01); C07D 519/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); C07D 487/04 (2013.01);
Abstract

Disclosed are compounds of Formula G1: where 'R'. 'R' to “R”, “n”, “m”, “p”, “W”, “X”, “Y”, and “Z” are defined herein, which compounds are antagonists of Areceptor. Disclosed herein also are uses of the compounds described herein as antagonists of the A2A receptor in the potential treatment or prevention of neurological disorders and diseases in which Areceptors are involved. Disclosed herein also are pharmaceutical compositions comprising these compounds and uses of these pharmaceutical compositions.


Find Patent Forward Citations

Loading…