The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 03, 2018
Filed:
Aug. 11, 2016
Applicant:
Reaction Biology Corp., Malvern, PA (US);
Inventors:
Haiching Ma, Malvern, PA (US);
Yuren Wang, Washington Crossing, PA (US);
Assignee:
REACTION BIOLOGY CORP., Malvern, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); A61K 31/437 (2006.01); A61K 45/06 (2006.01); C07D 409/12 (2006.01); A61K 31/4436 (2006.01); C07D 213/82 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); A61K 31/437 (2013.01); A61K 31/44 (2013.01); A61K 31/4436 (2013.01); A61K 45/06 (2013.01); C07D 213/82 (2013.01); C07D 409/12 (2013.01);
Abstract
The present invention relates to methods of modulating (for example inhibiting) activity of histone deacetylases (HDACs) and/or treating HDACs-associated diseases including, for example, cancers, inflammatory disorders, neurodegenerative disorders, etc. The invention also provides novel compounds and compositions thereof, methods of preparation of the same, as well as methods of use of the same for inhibition of HDACs and/or treatment of HDAC-associated diseases.