The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2018

Filed:

Apr. 20, 2017
Applicant:

The United States of America, As Represented BY the Secretary of Agriculture, Washington, DC (US);

Inventors:

Spencer S. Walse, Fresno, CA (US);

Daniel Kuzmich, Clovis, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/83 (2006.01); C07C 45/66 (2006.01); C07C 49/497 (2006.01); C07C 51/04 (2006.01); C07C 67/327 (2006.01); C07C 69/732 (2006.01); C07C 69/734 (2006.01); C07C 51/09 (2006.01);
U.S. Cl.
CPC ...
C07D 307/83 (2013.01); C07C 45/66 (2013.01); C07C 49/497 (2013.01); C07C 51/09 (2013.01); C07C 67/327 (2013.01); C07C 69/732 (2013.01); C07C 69/734 (2013.01); C07C 2601/14 (2017.05); C07C 2601/16 (2017.05);
Abstract

A process for the synthesis of trans-fused γ-lactones having Formula (IV) from substituted cyclic ketones having Formula (I). A diastereoselective synthesis of (±)-epianastrephin (1) (wherein: Ris ethenyl, Rand Ris methyl, and n is 1), (±)-anastrephin (2) (wherein: Ris ethenyl, Rand Ris methyl and n is 1), and analogs thereof (wherein: Ris H, Calkyl, Calkenyl or Calkynyl, Ris H, Calkyl, Calkenyl or Calkynyl, Rand Rtogether with the carbon atom they are attached form a Ccycloalkyl ring, Ris Calkyl and n is 0-2):


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