The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2018

Filed:

Aug. 08, 2017
Applicant:

Rosalind Franklin University of Medicine and Science, North Chicago, IL (US);

Inventors:

Grace E. Stutzmann, Lake Forest, IL (US);

Russell Dahl, North Chicago, IL (US);

Christopher H. Kaiho, North Chicago, IL (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/52 (2006.01); C07D 307/54 (2006.01); C07D 405/12 (2006.01); C07D 407/12 (2006.01);
U.S. Cl.
CPC ...
C07D 307/54 (2013.01); C07D 307/52 (2013.01); C07D 405/12 (2013.01); C07D 407/12 (2013.01);
Abstract

Disclosed herein are methods and compositions comprising compounds capable of normalizing neuronal calcium dyshomeostasis. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, Pick's disease, chronic traumatic encepholopathy, traumatic brain injury, stroke, cerebellar ataxia, multiple sclerosis, Down syndrome, and aging-related CNS disorders.


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