The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2018

Filed:

Aug. 26, 2014
Applicant:

Armo Biosciences, Inc., Redwood City, CA (US);

Inventors:

John Brian Mumm, Los Altos Hills, CA (US);

Ivan Ho Chan, Redwood City, CA (US);

Assignee:

ARMO BioSciences, Inc., Redwood City, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 45/06 (2006.01); A61K 31/397 (2006.01); A61K 31/455 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2066 (2013.01); A61K 31/397 (2013.01); A61K 31/455 (2013.01); A61K 45/06 (2013.01); C07K 2319/00 (2013.01);
Abstract

Methods of treating subjects having diseases, disorders, or conditions, including disorders associated with cholesterol homeostasis, responsive to IL-10, including methods of administration and dosing regimens associated therewith, are provided, More particularly, the present disclosure relates to optimized dosing parameters to achieve and maintain efficacy in the treatment and/or prevention of metabolic diseases, disorders and conditions in a subject, while minimizing the adverse effects associated therewith. Particular embodiments are directed to the treatment and/or prevention of abnormally high levels of cholesterol and/or manifestation(s) of hypercholesterolemia in as subject.


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