The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 2018

Filed:

May. 30, 2014
Applicants:

H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

John J. Heine, New Port Richey, FL (US);

Thomas A. Sellers, Tampa, FL (US);

Celine M. Vachon, Rochester, MN (US);

Erin E. Fowler, Tampa, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2006.01); G06T 7/00 (2017.01); G06K 9/52 (2006.01); A61B 6/00 (2006.01); G06K 9/62 (2006.01); G06T 7/41 (2017.01);
U.S. Cl.
CPC ...
G06T 7/0012 (2013.01); A61B 6/502 (2013.01); G06K 9/0051 (2013.01); G06K 9/527 (2013.01); G06K 9/623 (2013.01); G06T 7/41 (2017.01); G06K 2209/05 (2013.01); G06T 2207/10116 (2013.01); G06T 2207/20076 (2013.01); G06T 2207/30068 (2013.01);
Abstract

An automated percentage of breast density measure (PDa) that analyzes signal dependent noise (SDN) based on a wavelet expansion using full field digital mammography (FFDM). A matched case-control dataset is used with images acquired from a specific direct x-ray capture FFDM system. PDa is applied to the raw and clinical display representation images. Transforming (pixel mapping) of the raw image to another representation (raw-transformed) is performed using differential evolution optimization and investigated the influence of lowering the native spatial resolution of the image by a one-half. When controlling for body mass index, the quartile specific ORs for the associations of PDa with breast cancer varied with representation and resolution. PDa is a valid automated breast density measurement for a specific FFDM technology and compares well against PD (operator-assisted or the standard) when applied to either the raw-transformed or clinical display images from this FFDM technology.


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