The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 2018

Filed:

Jun. 23, 2014
Applicant:

Sophion Bioscience A/s, Ballerup, DK;

Inventors:

David Geraint Owen, Cambridge, GB;

Nicholas Gerard Byrne, Cambridge, GB;

Assignee:

SOPHION BIOSCIENCE A/S, Ballerup, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01); B01L 3/00 (2006.01); G01N 27/28 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
G01N 33/502 (2013.01); B01L 3/5025 (2013.01); G01N 27/28 (2013.01); G01N 33/48728 (2013.01); G01N 33/5438 (2013.01); G01N 33/6872 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0851 (2013.01); B01L 2300/0893 (2013.01); B01L 2300/16 (2013.01); G01N 2500/04 (2013.01); G01N 2500/10 (2013.01); Y10T 29/49826 (2015.01);
Abstract

The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.


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