The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2018
Filed:
Jan. 17, 2013
Hoffmann-la Roche Inc., Nutley, NJ (US);
Christof Fattinger, Blauen, CH;
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
A device for use in the detection of binding affinities comprises a planar waveguide () arranged on a substrate (), and an optical coupler () for coupling coherent light () of a predetermined wavelength into the planar waveguide. The coherent light propagates through the planar waveguide () with an evanescent field () propagating along an outer surface () of the planar waveguide. The outer surface () of the planar waveguide comprises binding sites () thereon capable of binding target samples () to the binding sites () such that light of the evanescent field () is scattered by target samples () bound to the binding sites (). The binding sites () are arranged along a plurality of predetermined lines () which are arranged such that the scattered light constructively interferes at a predetermined detection location with a difference in optical path length which is an integer multiple of the predetermined wavelength.