The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 2018

Filed:

Jun. 23, 2016
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

Lahey Clinic Foundation, Inc., Burlington, MA (US);

Inventors:

Michael J. Cima, Winchester, MA (US);

Gregory J. Ekchian, Belmont, MA (US);

Christophoros C. Vassiliou, Cambridge, MA (US);

Vincent H. Liu, Cambridge, MA (US);

Christoph Wald, Nahant, MA (US);

Sebastian Flacke, Nahant, MA (US);

Fredric D. Gordon, Newton, MA (US);

Assignees:

Massachusetts Institute of Technology, Cambridge, MA (US);

Lahey Clinic Foundation, Inc., Burlington, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/34 (2006.01); C12Q 1/70 (2006.01); G01N 33/53 (2006.01); G01N 1/34 (2006.01); A61F 2/01 (2006.01); G01N 33/543 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 1/34 (2013.01); A61F 2/01 (2013.01); G01N 33/5302 (2013.01); G01N 33/5306 (2013.01); G01N 33/54313 (2013.01); G01N 33/56983 (2013.01);
Abstract

Trapping devices and methods are provided for capturing a medical analyte, in blood or another biological fluid. The device may include a structural substrate and a binding agent, such as an antibody, affixed to the structural substrate, wherein the binding agent is capable of binding or attaching with a medical analyte, such as a viral particle, and the device is configured for placement in a biological cavity or vessel (containing a biological fluid) in a patient. The trapping device, which may be in a twisted coil shape, is configured to trap at least some of the medical analyte, such a viral particle, present in the biological fluid. The method may include deploying a trapping device into the patient's blood vessel; after a period following the deployment, removing the trapping device from the biological cavity or blood vessel; and then analyzing the trapping device for the presence of the medical analyte.


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