The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2018
Filed:
Mar. 28, 2012
Applicants:
Heidi Alexandra Lane, Therwil, CH;
Felix Bachmann, Basel, CH;
Inventors:
Heidi Alexandra Lane, Therwil, CH;
Felix Bachmann, Basel, CH;
Assignee:
BASILEA PHARMACEUTICA AG, Basel, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4245 (2006.01); A61K 31/4439 (2006.01); C12Q 1/48 (2006.01); G01N 33/574 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/485 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); G01N 33/57407 (2013.01); G01N 2440/14 (2013.01); G01N 2800/52 (2013.01);
Abstract
Use of phospho-Akt as a biomarker for predicting the response, such as resistance, to a compound, wherein phospho-Akt is Akt that has been phosphorylated on one or more residues, with the proviso that for Akt1, Akt2, and Akt3 the designation phospho-Akt is used to indicate phosphorylation at a site other than T308, T309 or T305 respectively, wherein the compound is a compound of general formula (I).