The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2018
Filed:
May. 23, 2014
Applicant:
Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, CN;
Inventors:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12P 7/46 (2006.01); C12R 1/19 (2006.01); C12N 15/52 (2006.01); C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
C12P 7/46 (2013.01); C12N 1/20 (2013.01); C12N 9/0051 (2013.01); C12N 15/52 (2013.01); C12R 1/19 (2013.01); C12Y 108/01004 (2013.01);
Abstract
The invention relates to the field of producing succinate byfermentation. Specifically, the invention provides an engineered recombinantfor producing succinate, wherein saidcontains one or more of the following modifications: a) enhanced activity of the protein(s) encoded by the gene(s) involved in pentose phosphate pathway (PPP), b) enhanced activity of the protein encoded by sthA gene, and optionally c) mutant lpdA gene. The invention also relates to use of the engineered recombinantfor producing succinate, and a method of using the engineered recombinantfor producing succinate.