The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 2018

Filed:

Aug. 28, 2013
Applicant:

Privi Biotechnologies Private Limited, Mumbai, Maharashtra, IN;

Inventors:

Manish Petkar, Mumbai, IN;

Shweta Pawar, Mumbai, IN;

Arvind M. Lali, Mumbai, IN;

Assignee:

PRIVI BIOTECHNOLOGIES PRIVATE LIMITED, Navi Mumbai, Maharashtra, IN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/14 (2006.01); A23L 29/30 (2016.01); C12P 7/18 (2006.01); C12N 1/16 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12P 7/18 (2013.01); C12N 1/16 (2013.01);
Abstract

The present invention utilizes yeast(NRRL 12968) for xylitol production, as an alternative and unexplored strain with high bioconversion rate and stability at higher initial xylose concentration. Different parameters are optimized for batch fermentation of xylose to xylitol such as initial xylose concentration, aeration (vvm), agitation (rpm), percent inoculum addition, and oxygen transfer rate. Maximum xylitol yield of 0.7 g/g of xylose is obtained with 3.33% inoculum, 250 g/l of initial xylose concentration, 0.2 vvm of aeration rate, and two stage agitation strategy comprising of 500 rpm for 0-24 hrs and 400 rpm for 24-72 hrs at not more than 72 hrs of fermentation time. The present invention coins a novel process mode of fermentation where the batch process is extended with continuous fermentation at optimum dilution rate of 0.02/hr with effective residence time of 52 hrs. Productivity of 'batch followed by continuous' process is 2.5 gm/lit/hr which is 1.34 times higher than batch and/or continuous process alone.


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