The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2018
Filed:
Jun. 28, 2016
Life Technologies Corporation, Carlsbad, CA (US);
Jason Dallwig, Eugene, OR (US);
David Hagen, Eugene, OR (US);
Ching-Ying Cheung, San Ramon, CA (US);
Gerald Thomas, Springfield, OR (US);
Stephen Yue, Eugene, OR (US);
LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US);
Abstract
Cyanine dye compounds having a substituted methine moiety that are nucleic acid stains, particularly for fluorescent staining of RNA, including compounds having the formula where Ris a C-Calkyl, sulfoalkyl, carboxyalkyl or C-Calkoxy; each Ris independently selected from the group consisting of H, C-Calkyl, C-Calkoxy, fused benzo, trifluoromethyl, amino, sulfo, carboxy and halogen, that is optionally further substituted; at least one of R, R, and Ris an alkyl, aryl, heteroaryl, cyclic, or heterocyclic moiety that is optionally substituted by alkyl, amino, aminoalkyl, carboxy, nitro, or halogen; and the remaining R, Ror Rare hydrogen; X is S, O, or Se; and D is a substituted or unsubstituted pyridinium, quinolinium or benzazolium moiety.