The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 26, 2018

Filed:

Nov. 13, 2015
Applicants:

Tinya Abrams, Acton, MA (US);

Steven Bruce Cohen, San Diego, CA (US);

Jason Damiano, Oakland, CA (US);

Clemens Dürr, Weil am Rhein, DE;

Thomas Huber, Allschwil, CH;

Daniel Menezes, Berkeley, CA (US);

Kathy Miller, San Francisco, CA (US);

Katherine Rendahl, Berkeley, CA (US);

Jean-michel Rene Rondeau, Rixheim, FR;

Inventors:

Tinya Abrams, Acton, MA (US);

Steven Bruce Cohen, San Diego, CA (US);

Jason Damiano, Oakland, CA (US);

Clemens Dürr, Weil am Rhein, DE;

Thomas Huber, Allschwil, CH;

Daniel Menezes, Berkeley, CA (US);

Kathy Miller, San Francisco, CA (US);

Katherine Rendahl, Berkeley, CA (US);

Jean-Michel Rene Rondeau, Rixheim, FR;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 47/68 (2017.01); C07K 16/30 (2006.01); A61K 31/53 (2006.01); A61K 31/5365 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 31/5365 (2013.01); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); C07K 16/30 (2013.01); G01N 33/57492 (2013.01); C07K 2299/00 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/52 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01); G01N 2333/705 (2013.01);
Abstract

This application discloses anti-P-cadherin antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments. The invention also relates to methods of treating cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.


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