The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2018
Filed:
Feb. 15, 2012
Applicants:
Matthew J. Giacalone, San Diego, CA (US);
Michael J. Newman, San Diego, CA (US);
Inventors:
Matthew J. Giacalone, San Diego, CA (US);
Michael J. Newman, San Diego, CA (US);
Assignee:
VAXIION THERAPEUTICS, LLC, San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/195 (2006.01); C12N 1/02 (2006.01); C12N 1/20 (2006.01); C12N 15/00 (2006.01); C12N 15/10 (2006.01); C07K 16/00 (2006.01); C12N 15/70 (2006.01); C12N 15/74 (2006.01);
U.S. Cl.
CPC ...
C07K 14/195 (2013.01); C07K 16/00 (2013.01); C12N 1/02 (2013.01); C12N 1/20 (2013.01); C12N 15/00 (2013.01); C12N 15/1037 (2013.01); C12N 15/70 (2013.01); C07K 2319/00 (2013.01); C07K 2319/705 (2013.01); C12N 15/74 (2013.01);
Abstract
The present application relates to the use of bacterial minicells as targeted delivery agents in vivo and in vitro. Described herein are genetically engineered eubacterial minicells designed to preferentially target and deliver therapeutically relevant agents using a minicell surface coupling molecule capable of binding and displaying antibodies or other Fc-containing targeting moiety fusions and conjugates.