The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2018
Filed:
Aug. 17, 2016
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Raymond J. Deshaies, Pasadena, CA (US);
Jing Li, Arcadia, CA (US);
Seth Cohen, San Marcos, CA (US);
Christian Perez, La Jolla, CA (US);
Yuyong Ma, San Diego, CA (US);
Assignees:
California Institute of Technology, Pasadena, CA (US);
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/54 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07D 215/54 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01);
Abstract
Candidate compounds for specific inhibition of Rpn11 are represented by Formula 1 where each of R, R, R, R, R, and Ris independently selected from hydrogen (H), substituted and unsubstituted alkyl groups, carboxyl groups, or substituted and unsubstituted carboxyamides.