The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2018
Filed:
Feb. 18, 2014
Applicant:
University of Pittsburgh—of the Commonwealth System of Higher;
Inventors:
Stephen F. Badylak, Pittsburgh, PA (US);
Donald Freytes, Pittsburgh, PA (US);
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 35/37 (2015.01); A61L 27/36 (2006.01); A61K 35/12 (2015.01); A61L 27/34 (2006.01); A61L 27/38 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); C12P 21/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3633 (2013.01); A61K 35/12 (2013.01); A61L 27/34 (2013.01); A61L 27/3687 (2013.01); A61L 27/38 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); C12P 21/06 (2013.01); A61K 38/00 (2013.01); A61L 2300/64 (2013.01); A61L 2400/06 (2013.01); A61L 2420/04 (2013.01);
Abstract
Provided are methods for preparing gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.