The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2018
Filed:
Nov. 05, 2013
Applicant:
Vtv Therapeutics Llc, High Point, NC (US);
Inventors:
Maria Carmen Valcarce Lopez, Oak Ridge, NC (US);
Tung Fong, Somerset, NJ (US);
Assignee:
vTv Therapeutics LLC, High Point, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/22 (2006.01); A61K 38/26 (2006.01); A61K 45/06 (2006.01); A61K 31/426 (2006.01); A61K 31/4985 (2006.01);
U.S. Cl.
CPC ...
A61K 38/22 (2013.01); A61K 31/426 (2013.01); A61K 31/4985 (2013.01); A61K 38/26 (2013.01); A61K 45/06 (2013.01);
Abstract
The present invention relates to pharmaceutical compositions comprising {2-[3-cyclohexyl-3-(trans-4-propoxy-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid (FRI-1) in combination with an anti-diabetic drug selected from the group consisting of metformin, sitagliptin or exenatide. The present invention also relates to the use of the pharmaceutical compositions in restoring insulin sensitivity and treating type II diabetes, including reducing body weight in subjects undergoing type II diabetes treatment.