The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 26, 2018
Filed:
Mar. 27, 2015
Applicant:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Inventors:
Christopher S. Burgey, Ambler, PA (US);
Jeffrey F. Fritzen, Pottstown, PA (US);
Jaume Balsells, North Wales, PA (US);
Mehul Patel, Blue Bell, PA (US);
Assignee:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/06 (2006.01); C07D 237/22 (2006.01); C07D 239/47 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/513 (2006.01); A61P 31/18 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 31/501 (2013.01); A61K 31/513 (2013.01); A61K 45/06 (2013.01); C07D 237/22 (2013.01); C07D 239/47 (2013.01); C07D 403/06 (2013.01);
Abstract
Compounds of Formula I are described: wherein Rand Rare defined herein. The compounds of Formula I are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV, and the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.