The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 19, 2018
Filed:
Jun. 24, 2016
Celgene Corporation, Summit, NJ (US);
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Office of Technology Transfer, National Institutes of Health, Washington, DC (US);
Robert Yarchoan, Bethesda, MD (US);
Jerome B. Zeldis, Princeton, NJ (US);
Mark N. Polizzotto, New South Wales, AU;
David A. Davis, Bethesda, MD (US);
Irini Sereti, Washington, DC (US);
Thomas S. Uldrick, Washington, DC (US);
Denise Whitby, Frederick, MD (US);
Vikram Khetani, Short Hills, NJ (US);
Celgene Corporation, Summit, NJ (US);
The United States of America, as Represented by the Secretary, Department of Health and Human Services, Washington, DC (US);
Abstract
Provided herein are uses of gene and protein biomarkers as a predictor of clinical sensitivity of Kaposi's sarcoma (KS) or Kaposi's sarcoma-associated herpesvirus (KSHV) induced lymphoma and patient response to treatment with an immunomodulatory compound. Further provided herein are methods for the treatment or management of Kaposi's sarcoma or KSHV-induced lymphoma with an immunomodulatory compound, alone or in combination with doxorubicin.