The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 19, 2018
Filed:
Jan. 27, 2015
Beijing Stomatology Hospital, Capital Medical University, Beijing, CN;
Beijing Sh Bio-tech Corporation, Beijing, CN;
Songling Wang, Beijing, CN;
Zuze Wu, Beijing, CN;
Yu Cao, Beijing, CN;
Hua Wang, Beijing, CN;
Yi Liu, Beijing, CN;
Jinsong Wang, Beijing, CN;
Jingchao Hu, Beijing, CN;
Jianjin Bi, Beijing, CN;
Yilin Xie, Beijing, CN;
Wenqiang An, Beijing, CN;
Beijing Stomatology Hospital, Capital Medical University, Beijing, CN;
Beijing SH Bio-Tech Corporation, Beijing, CN;
Abstract
Provided in the present invention are odontogenic stem cells and a use of genetically modified odontogenic stem cells for treating periodontal disease, repairing defects in periodontal bone tissues or soft tissues and/or promoting the regeneration of periodontal tissues, or in products for treating acute and chronic bone tissue injuries (e.g. bone fracture) or bone tissue defects. Also provided in the present invention is a composition comprising odontogenic stem cells and/or genetically modified odontogenic stem cells, wherein an exogenous hepatocyte growth factor gene is introduced into odontogenic stem cells through an adenovirus or adeno-associated virus vector to obtain the genetically modified odontogenic stem cells.