The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2018

Filed:

Jul. 15, 2013
Applicants:

Institut National DE LA Sante ET DE LA Recherche Medicale, Paris, FR;

Universite Paris Descartes, Paris, FR;

Inventors:

Xavier Nassif, Paris, FR;

Sandrine Bourdoulous, Paris, FR;

Olivier Join-Lambert, Paris, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/095 (2006.01); C07K 14/705 (2006.01); C07K 14/22 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 39/40 (2006.01); C12N 15/113 (2010.01); G01N 33/50 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70503 (2013.01); A61K 39/095 (2013.01); A61K 39/3955 (2013.01); A61K 39/40 (2013.01); C07K 14/22 (2013.01); C07K 14/70596 (2013.01); C07K 16/2803 (2013.01); C12N 15/1138 (2013.01); G01N 33/5041 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); C07K 2319/30 (2013.01); C07K 2319/32 (2013.01); C12N 2310/11 (2013.01); G01N 2333/195 (2013.01); G01N 2333/70596 (2013.01); G01N 2500/02 (2013.01); G01N 2500/10 (2013.01);
Abstract

The present invention concerns the use of an inhibitor of an interaction between type IV pilus-associated protein and CD147 for preventing or treating meningoccal bacteraemia and/or infection. The present invention also relates to the combined use of such inhibitor and of an anti-bacterial compound, such as one used to prevent or treat a meningococcal infection. The invention also relates to a method for the prevention and/or treatment of meningococcal bacteraemia and/or infection, and to a method for screening inhibitors of the interaction between type IV pilus-associated protein and CD147.


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