The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10000521 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 19, 2018

Filed:

Mar. 15, 2014
Applicant:

Nucorion Pharmaceuticals, Inc., Wilmington, DE (US);

Inventors:

Zucai Suo, Dublin, OH (US);

Vinod P. Vyavhare, Columbus, OH (US);

David J. Taggart, Columbus, OH (US);

Assignee:

Nucorion Pharmaceuticals, Inc., Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); A01N 43/04 (2006.01); C07H 19/00 (2006.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01); C07H 19/06 (2006.01); A61K 31/7052 (2006.01); A61K 31/7068 (2006.01);
U.S. Cl.
CPC ...
C07H 19/06 (2013.01); A61K 31/7052 (2013.01); A61K 31/7068 (2013.01);
Abstract

In one aspect, the invention relates to substituted gemcitabine aryl amide analogs, derivatives thereof, and related compounds; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating viral disorders and disorders of uncontrolled cellular proliferation using the compounds and compositions. In certain aspects, the compounds have the following structure:


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