The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 19, 2018
Filed:
Feb. 12, 2016
Applicant:
Opko Health, Inc., Miami, FL (US);
Inventors:
Ingrid Mergelsberg, Mahwah, NJ (US);
Dominik Hermann Scherer, Horw, CH;
Monika Erika Huttenloch, Kriens, CH;
Hon-Chung Tsui, East Brunswick, NJ (US);
Sunil Paliwal, Monroe Township, NJ (US);
Neng-Yang Shih, Lexington, MA (US);
Assignee:
OPKO Health, Inc., Miami, FL (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/10 (2006.01); C07D 211/38 (2006.01); C07D 498/10 (2006.01); C07D 211/56 (2006.01);
U.S. Cl.
CPC ...
C07D 471/10 (2013.01); C07D 211/38 (2013.01); C07D 211/56 (2013.01); C07D 498/10 (2013.01);
Abstract
This application discloses a process to synthesize 8-({1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy)-methyl]-8-pheny-1,7-diazaspiro[4.5]decan-2-one comprising reacting a compound of the Formula 27a-sulfonate with zinc in the presence of acetic acid.