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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10000464 B1

PDFFull Text
Date of Patent:
Jun. 19, 2018

Filed:

Oct. 27, 2016

Process for preparing 3-[(4s)-8-bromo-1-methyl-6-(2-pyridinyl)-4h-imidazo[1,2-a][1,4]benzodiazepine-4-yl]propionic acid methyl ester or the benzene sulfonate salt thereof, and compounds useful in that process

Applicant:

Paion Uk Limited, Cambridge, Cambridgeshire, GB;

Inventors:

Gary Stuart Tilbrook, Huntingdon, GB;

Andreas Schumacher, Efringen-Kirchen, DE;

Rene Emmenegger, Basel, CH;

Assignee:

PAION UK LIMITED, Cambridge, Cambridgeshire, GB;

Attorney:

Mintz Levin Cohn Ferris Glovsky and Popeo, PC

Primary Examiner:

Brenda L Coleman

Int. Cl.
CPC ...
C07D 213/55 (2006.01); C07D 401/04 (2006.01); C07D 213/40 (2006.01); C07D 487/04 (2006.01); C07F 9/6558 (2006.01); C07D 213/50 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); C07D 213/40 (2013.01); C07D 213/50 (2013.01); C07D 487/04 (2013.01); C07F 9/65586 (2013.01);
Abstract

The invention concerns a new process for preparing 3-[(4S)-8-bromo-1-methyl-6-(2-pyridinyl)-4H-imidazo[1,2-a][1,4]benzodiazepine-4-yl]-propionic acid methyl ester or with an oxidizing agent and optionally treating the reaction product under acidic conditions, such as to produce the compound of formula (F) or the compound (P), and new compounds useful as starting materials or as intermediates for performing that process.

Find Patent Forward Citations

Tilbrook, Gary. (2018). Process for preparing 3-[(4s)-8-bromo-1-methyl-6-(2-pyridinyl)-4h-imidazo[1,2-a][1,4]benzodiazepine-4-yl]propionic acid methyl ester or the benzene sulfonate salt thereof, and compounds useful in that process (U.S. Patent No. 10000464). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10000464

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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