The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 19, 2018
Filed:
Jul. 15, 2017
Applicant:
Sri International, Menlo Park, CA (US);
Inventors:
Ling Jong, Menlo Park, CA (US);
Chih-Tsung Chang, Menlo Park, CA (US);
Jaehyeon Park, Menlo Park, CA (US);
Assignee:
SRI International, Menlo Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/02 (2006.01); A61K 31/404 (2006.01); C07D 209/14 (2006.01); C07D 209/12 (2006.01); C07D 405/02 (2006.01);
U.S. Cl.
CPC ...
C07D 209/14 (2013.01); A61K 31/404 (2013.01); C07D 209/12 (2013.01); C07D 403/02 (2013.01); C07D 405/02 (2013.01);
Abstract
The invention provides mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) inhibitors, and pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant diminution of tumor cell growth, cancer or metastasis.