IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10000450 B1

PDFFull Text
Date of Patent:
Jun. 19, 2018

Filed:

Feb. 16, 2017

N,n-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors

Applicant:

Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Muneaki Kurimura, Tokushima, JP;

Shinichi Taira, Tokushima, JP;

Takahiro Tomoyasu, Tokushima, JP;

Nobuaki Ito, Tokushima, JP;

Kuninori Tai, Tokushima, JP;

Noriaki Takemura, Tokushima, JP;

Takayuki Matsuzaki, Tokushima, JP;

Yasuhiro Menjo, Tokushima, JP;

Shin Miyamura, Tokushima, JP;

Yohji Sakurai, Tokushima, JP;

Akihito Watanabe, Tokushima, JP;

Yasuyo Sakata, Tokushima, JP;

Takumi Masumoto, Tokushima, JP;

Kohei Akazawa, Tokushima, JP;

Haruhiko Sugino, Tokushima, JP;

Naoki Amada, Tokushima, JP;

Satoshi Ohashi, Tokushima, JP;

Tomoichi Shinohara, Tokushima, JP;

Hirofumi Sasaki, Tokushima, JP;

Chisako Morita, Tokushima, JP;

Junko Yamashita, Tokushima, JP;

Satoko Nakajima, Tokushima, JP;

Assignee:

OTSUKA PHARMACEUTICAL CO., LTD., Chiyoda-ku, Tokyo, JP;

Attorney:

Sughrue Mion, PLLC

Primary Examiner:

Michael Barker

Int. Cl.
CPC ...
C07D 207/14 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 401/14 (2006.01); C07D 471/04 (2006.01); C07D 495/04 (2006.01); A61K 31/40 (2006.01); A61K 31/4025 (2006.01); C07D 205/04 (2006.01); C07D 409/14 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 205/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 409/14 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 495/04 (2013.01);
Abstract

The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein Rand Rare each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.

Find Patent Forward Citations

Loading…