Company Filing History:
Years Active: 2024-2025
Title: Seiyu Hosono: Innovator in Spatial Multiomics Technology
Introduction
Seiyu Hosono is a prominent inventor based in Stoneham, MA (US). He has made significant contributions to the field of spatial multiomics, focusing on advanced microscopy imaging techniques. His work is crucial for understanding the complexities of tissue heterogeneity, particularly in the context of tumor microenvironments.
Latest Patents
Seiyu Hosono holds 2 patents that showcase his innovative approaches. His latest patents include a method and instrumentation for spatial multiomics using SUMI-technology. This technology allows for the spatial resolution of multiple mRNAs, proteins, and metabolites at a subcellular level, providing valuable molecular information. The SUMI-Seq method combines Spatial Unique Molecular Identifier in situ sequencing with in vitro sequencing of rolonies derived from rolling circle amplification. This method overcomes limitations in transcript quantity and sequence length analysis. Additionally, he has developed a method that combines single-cell gene expression mapping with targeted RNA or cDNA sequencing using padlock oligonucleotides. This method, known as Fly FISH, utilizes padlock oligonucleotides as fluorescence in situ hybridization probes for detecting and sequencing targeted RNA or cDNA transcripts.
Career Highlights
Seiyu Hosono is currently associated with Miltenyi Biotec B.V. Co., Kg, where he continues to push the boundaries of scientific research. His work has been instrumental in advancing methodologies that enhance our understanding of molecular development and disease treatment.
Collaborations
Seiyu has collaborated with notable colleagues, including Robert Pinard and Thomas Rothmann, to further his research and innovations in the field.
Conclusion
Seiyu Hosono's contributions to spatial multiomics technology are paving the way for new insights into molecular biology and disease treatment. His innovative methods and collaborative efforts are essential for advancing scientific knowledge in this critical area.
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