University of Guelph

Azad Kumar Kaushik

Éva Nagy

Davor Ojkic

Bryan Griffin

Madhuri Koti

Helena Grgic

Juan Carlos Corredor

James Ackford

Yanlong Pei

Peter J Krell

A high level replication fowl adenovirus (FAdV) isolate capable of reaching a viral titer of at least 3 log 10 is described. Said FAdV is a non-pathogenic strain of fowl adenovirus serotype 4, identified as FAdV-4 ON1. Additionally, the present disclosure also provides a viral vector comprising the fowl adenovirus, which has inserted an exogenous nucleotide sequence coding for at least one antigenic site of a disease of concern, as well as a method for obtaining said viral vector and an immunogenic composition comprising the same.

Non-pathogenic serotype 4 fowl adenovirus (fadv-4) and viral vector thereof

The present disclosure describes a single chain variable fragment (scFv) that binds BHV-1 virus comprising a light chain variable region, a linker and a heavy chain variable region. The disclosure also describes nucleic acid molecules encoding the scFv molecules, methods and uses thereof for treating or neutralizing BHV-1 infection and diagnostic methods, agents and kits thereof.

Engineered scFv against bovine herpes virus type I

Growing community of inventors

Guelph, Canada

Éva Nagy