Plexxikon Inc.

Opna Bio Sa

Opna Immuno-oncology Sa

Zuojun Guo

Wayne Spevak

Jiazhong Zhang

John Buell

Ying Zhang

Guoxian Wu

Chao Zhang

Songyuan Shi

Phuongly Pham

Aaron Edward Albers

Hannah Powers

Jack Walleshauser

Jeffrey Yung Wu

Cuong Q Ly

Mark Vander Wal

Aaron Albers

Prabha N Ibrahim

Jack Lin

Hiroaki Inagaki

Yongil Jin

Jeffrey Wu

Compounds and methods for CD73 modulation and indications therefor

Compounds and methods for EP300 or CBP modulation and indications therefor

Disclosed are compounds of Formula (I) and (Ia): 

Compounds and methods for IDO and TDO modulation, and indications therefor

Disclosed are compounds of Formula I(a): 

Disclosed are compounds having a compound of Formula I: or a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, compositions thereof, and uses thereof.

Compounds and methods for kinase modulation

Disclosed are compounds of Formula I(b): or a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, wherein Ring A, Ring HD, J, each T, R, R, R, each R, and m are as described in any of the embodiments described in this disclosure; compositions thereof; and uses thereof.

Compounds and methods for kinase modulation, and indications therefor

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Pasadena, CA, United States of America

Zuojun Guo