Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Zsuzsa Visky Nee Gombos

Csaba Szantay

Gabor Kovacs

Istvan Szekely

Istvan Stadler

Vilmos Simonidesz

Istvan Tomoskozi

Marianna Lovasz Nee Gaspar

Julia Remport Nee Radoczi

Borbala Keresztesnee Ordog

Borbala Keresztes Nee Ordog

A process for the preparation of optically active or racemic lactone diol derivatives of the formula ##STR1## (for use as intermediates in the Corey prostaglandin synthesis). Optically active or racemic lactone diol derivatives are inclosed, in which

Process for making bicyclic lactone derivatives for use as intermediates

A compound of the formula is disclosed. ##STR1## wherein R.sup.3 and R.sup.4 are the same or different and are each hydrogen, lower alkanoyl, lower alkanoyl substituted by 1, 2, or 3 halogen atoms, or R.sup.3 and R.sup.4 together form an ##STR2## group in which R.sup.5 and R.sup.6 are the same or different and are each hydrogen, alkyl or aryl as well as a process for the preparation thereof.

Bicyclic lactone derivatives employed as intermediates in the synthesis

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Budapest, Hungary

Zsuzsa Visky Nee Gombos