Aclara Biosciences, Inc.

Soane Biosciences, Inc.

Other

The Dow Chemical Company

Corning Precision Lens, Inc.

Soane Technologies, Inc.

Monogram Biosciences, Inc.

Zoya M Soane

David S Soane

Herbert H Hooper

M Goretty Amigo

M Goretty Alonso Amigo

Devices and methods are disclosed for moving charged molecules through a medium by the application of a plurality of electrical fields of sufficient strength and applied for sufficient amounts of time so as to move the charged molecules through the medium. The devices although preferably small in size, preferably generate large numbers (100 or more) of electrical fields to a movement area which preferably contains a liquid buffered or gel medium. Mixtures of charged molecules are pulled through the gel by the force of the electrical fields. The fields are preferably activated simultaneously or sequentially one after another at various speeds to create complex force field distributions or moving field waves along the separation medium. Charged molecules capable of moving quickly through the gel will be moved along by the faster moving field waves and be separated from slower moving molecules. The fields can be activated by computer software and can be used to move molecules away from and toward each other to obtain rapid and complex chemical synthesis, sequencing or reaction protocols.

Method for moving charged particles

Device and method for moving charged particles

Polycarbonate electrophoretic devices

Method and device for performing chemical reactions

Coupling fluids for use in optically coupling a projection lens system of a projection television to a cathode ray tube (CRT (16)) are provided. The fluids have: (1) at least one polymer having a siloxane backbone, i.e., at least one polymer having a &mdash;Si&mdash;O&mdash;Si&mdash;O&mdash;Si&mdash; backbone, and (2) methyl, phenyl, and hydrophilic groups attached to the silicon atoms of the backbone. The fluid can be composed of a single siloxane polymer having methyl, phenyl, and hydrophilic side groups or a mixture of a siloxane polymer having methyl and phenyl side groups with a siloxane polymer having methyl and hydrophylic side groups. The index of refraction of the fluid is preferably greater than 1.52 so as to minimize reflections at the interface between the fluid and the faceplate (17) of the CRT (16).

Coupler fluids for projection televisions

Methods are provided for the fabrication of polymeric microchannel structures having enclosed microchannels of capillary dimension. The microchannel structures are constructed of a base plate and a cover, sealed together. Microchannel structures having walls of a plastic material are formed in a generally planar surface of at least the base plate. The cover has at least one generally planar surface, and the microchannel structures are enclosed by bonding the planar surfaces of the cover and the base plate together. In some embodiments the surfaces of the cover and base plate are both of plastic material, and are directly thermally bonded. In some embodiments a bonding material is applied to one of the surface prior to bringing the surfaces together. Suitable bonding materials are disclosed.

Methods for fabricating enclosed microchannel structures

Method and device for moving molecules by the application of a plurality

Microchannels having at least an acrylic inner surface and methods of their use in electrophoretic applications are provided. The subject microchannels may be in the form of a variety of configurations suitable for holding an electrophoretic medium. The subject microchannels give rise to substantially reduced EOF and/or adsorption as compared to fused silica under conditions of electrophoresis and find use in a variety of electrophoretic applications in which charged entities are moved through a medium under the influence of the an applied electric field.

Acrylic microchannels and their use in electrophoretic applications

The present invention provides a gel-matrix whose electrical and/or thermal conductivity undergoes a significant change in response to minor variations in one of several externally controlled thermodynamic parameters, such as temperature, pH, ionic strength, and solvent composition. The matrix is formed by at least three primary components: conductive particles, swellable and deswellable crosslinked particles, and a solvent system. In the de-swollen state, the gel particles occupy a relatively small volume fraction of the gel-matrix, allowing the conductive particles to be discrete, fully suspended, and free flowing in the solvent system. Upon switching to the swollen state, the interstitial volume between the crosslinked gel particles diminishes, forcing the conductive particles to come into intimate contact with one another, thus creating a conductive percolation network. As a result, the electrical and/or thermal conductivity of the matrix is increased appreciably, because the interparticle connectivity among the conductive particles governs the electrical and/or thermal conductivity of the composite article. The conductivities exceed prior formulations with similar rheological characteristics, making such composite articles ideal for a number of specialized applications. Temperature-, pH-, ionic-strength-, and solvent-composition-sensitive switchable media are therefore prepared.

Conductive composite articles based on expandable and contractible

Growing community of inventors

Piedmont, CA, United States of America

Zoya M Soane