Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Zoltan Vargay

Tamas Szuts

Vera Gergely

Katalin Kaloy

Agnes Stadler Nee Szoke

Viktor Weiszfeiler

Jozsef Szejtli

Josef Szejtli

Laszlo Otvos

Tivadar Palagyi

Sandor Mlinko

Dezso Banfi

Karoly Payer

Istvan Gacs

Emilia Dobis Nee Farkas

The invention relates to the inclusion complexes of 7-isopropoxy-isoflavon formed with cyclodextrin or cyclodextrin derivatives as well as to the pharmaceutical compositions containing these inclusion complexes as active ingredient. The invention further relates to the preparation of the new inclusion complexes. The new inclusion complex according to the invention shows higher dissolution and resorption properties as compared to the active ingredient administered per se.

Inclusion complex of 7-isopropoxy-isoflavon formed with cyclodextrin,

The invention relates to the inclusion complexes of 7-isopropoxy-isoflavone formed with cyclodextrin or cyclodextrin derivatives as well as to the pharmaceutical compositions containing these inclusion complexes as active ingredient. The invention further relates to the preparation of the new inclusion complexes. The new inclusion complex according to the invention shows higher dissolution and resorption properties as compared to the active ingredient administered per se.

A process for measuring the isotope content of substances containing .sup.3 H or .sup.3 H and .sup.14 C isotopes in the gas phase, by converting the hydrogen content of the sample into water and the carbon content of the sample to a gaseous substance in simultaneous oxidation processes, separating the formed water and carbon dioxide, reconverting the .sup.3 H content of the water into gaseous form, introducing the gases containing .sup.3 H and possibly also .sup.14 C separately into a detecting unit, and determining the radioactivity of said gases, in which the tritium content of the water carrying the .sup.3 H radio-activity is bonded on a contact catalyst capable of water retention or adsorption and containing activated hydrogen, the gaseous mixture, containing also .sup.14 CO.sub.2 when a sample of .sup.14 C content is analyzed, is removed and, optionally after purification, is fed into a detecting unit together with a counting gas, then the tritium adsorbed on the surface of the catalyst is continuously converted into gas phase by exchange reaction with an appropriate gas flow and is fed into a detecting unit in unchanged state, or in the form of a compound prepared from it by chemical reaction.

Process and apparatus for measuring the isotope content of substances

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Budapest, Hungary

Zoltan Vargay