Egyt Gyogyszervegyeszeti Gyar

Egis Gyogyszergyar

Egis Gyogyszergyar Rt.

Other

Egis Pharmaceutical

Zoltan Budai

Tibor Mezei

Lujza E Petocz

Aranka Lay Nee Konya

Klara Reiter Nee Esses

Gabor Blasko

Katalin Grasser

Eniko Szirt Nee Kiszelly

Gyula Simig

Marton Fekete

Gabor Gigler

Istvan Gacsalyi

Ibolya Kosoczky

Karoly Magyar

Attila Kis-Tamas

Katalin Szemeredi

Attila Mandi

Istvan Gyertyan

Andras Egyed

Maria Szecsey Nee Hegedus

Pal Benko

Ildiko Ratz Nee Simonek

Jozsef Kelemen

Zoltan Vig

Eva Rakoczy Nee Pinter

Imre Klebovich

Eva Schmidt

Gizella Zsila

Attila Nagy

Ferenc Jurak

Eva Furdyga

Laszlo Puskas

Laszlo Kapolnai

Lajos Fekete

Judit Bajnogel

Valeria Hoffmann

Zoltan Vigh

Jozsef Reiter

Kalman Nagy

Gyula Lukacs

Peter Gorog

Eniko Kiszelly

Margit Csorgo

Laszlo Magdanyi

Endre Rivo

Zsuzsanna Orr

Viktor Andriska

Klara Kazo Nee Daroczi

Enik Szirt Nee Kiszelly

Ilona Sztruhar

Miklos Abermann

Istvan Gertyan

Eniko Sziri Nee Kiszelly

Agnes Sokorai

Aranka Lay

Erzsebet Kaufmanne Bojti

Laszlo Koncz

Agnes Sokorai Nee Janki

Terez Zubovits Nee Kristof

Andras Bilkei Gorzo

Ludmilla Rohacas Nee Zamkovaja

Katalin Baloghne Nemes

Judit Szego

Gyula Grezal

Gyongyi Vereczkey Nee Donath

Laszlo Kosa

Eniko Sziri neKiszelly

Luiza Petocz

Eniko Szirt Nee Kislelly

Aniko Kovacs

Kalara Reiter Nee Esses

Erika Karaffa

Klara Reiter Nee Eszes

1,7,7-trimethyl-bicyclo[2.2.1]heptane derivatives as anxiolytic agents

The invention refers to a pharmaceutical composition, a process for the preparation thereof and a novel medical use of bicycloheptane derivatives. The pharmaceutical compositions of the invention comprise a bicycloheptane derivative of the formula I ##STR1## wherein said derivative is as defined in the specification herein. The pharmaceutical compositions of the invention are suitable for the treatment of diseases and disorders that are connected with the influence on the cholecystokinin system, especially for preventing the spastic contraction of the gallbladder.

Pharmaceutical compositions containing bicycloheptane ether amines and a

The invention refers to pharmaceutical compositions for the prevention and/or treatment of gastrointestinal diseases connected with infections caused by Helicobacter pylori and a method for the treatment of such diseases. The pharmaceutical composition of the invention comprises as active ingredient a cyclic ketone derivative of the formula I ##STR1## wherein and R.sup.1 mean independently hydrogen or halo;

Pharmaceutical compositions for the prevention and/or treatment a

The invention relates to novel, pharmaceutically active trisubstituted cycloalkane derivatives, a process for the preparation thereof and pharmaceutical compositions comprising the same. The invention also encompasses the use of the said cycloalkane derivatives for the treatment of diseases and for the preparation of pharmaceutical compositions suitable for the treatment of diseases. The compounds according to the invention are characterized by the general formula (I), ##STR1## wherein R represents hydrogen, C.sub.1-4 alkyl or hydroxyl,

Trisubstituted cycloalkane derivatives and process for the preparation

Novel basic ether of general formula (I), ##STR1## wherein R.sup.1 and R.sup.2 are independently hydrogen, halogen or C.sub.1-4 alkoxy, or together they represent a 3,4-methylenedioxy group,

Basic ethers and process for the preparation thereof

Process for the preparation of 8 -[4 -[4-(pyrimidine-2-yl)-piperazine-1-yl]-butyl]-8-aza-spiro[4.5]decane-7,9-d ione (buspiron) of the Formula I ##STR1## and the hydrochlorides thereof having high purity by continuously adding a solution of 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]-but-2 -inyl]-8-aza-spiro[4.5]decane-7,9-dione of the formula II ##STR2## formed with an inert organic solvent having a concentration of at least 40% by weight to a suspension of a hydrogenation catalyst in an inert organic solvent and optionally converting the 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]-butyl]-8-aza-spiro[4.5]decane-7 ,9-dione thus obtained into the hydrochloride thereof.

Process for the preparation of high purity buspiron and the

The invention relates to novel, pharmaceutically active benz[e]indene derivatives, a process for the preparation thereof, pharmaceutical compositions comprising the same, further to the use of the said benz[e]indene derivatives in the treatment of certain diseases and in the preparation of pharmaceutical compositions suitable for the treatment of said diseases. The new benz[e]indene derivatives according to the invention correspond to the general formula ##STR1## wherein A represents a group of the formula alk-NR.sup.1 R.sup.2, wherein alk represents a C.sub.2-7 alkylene group optionally carrying a hydroxy substituent,

Benz[e]indene derivatives

The invention relates to new thioacid amide derivatives, a process for the preparation thereof, compositions, particularly feed additives, premixes and ready-for-use fodders, comprising the same, further to a method for increasing weight gain and improving fodder utilization of domestic animals. The new thioacid amide derivatives of the general formula (I), wherein

Thioacid amide derivatives and fodder compositions containing the same

The invention relates to novel racemic or optically active aminopropanol derivatives of formula I ##STR1## wherein R and R.sup.1 are independently hydrogen atom, halogen atom, lower alkoxy, or together represent a methylene dioxy group,

Aminopropanol derivatives, process for their preparation and

This invention relates to fodder compositions, particularly feed additives, premixes and ready-for-use fodders, and a method for increasing weight-gain and improving fodder utilization of dimestic animals. The compositions according to the invention comprise as active ingredient a compound of the general formula (I), ##STR1## wherein R.sup.1 represents methoxy or hydrogen and

Fodder compositions

This invention relates to novel triazolopyrimidine derivatives of formulae (Ia) and (Ib), ##STR1## wherein Q represents hydrogen, a heterocyclic group optionally substituted by a C.sub.1-4 alkyl group and containing one or more oxygen and/or nitrogen atoms or a group of formula

Novel triazolo-pyrimidine derivatives

The new compounds of the general Formula I ##STR1## (wherein A stands for a C.sub.2-4 straight or branched chain alkylene group;

Substituted styrene derivatives

The invention relates to selected stereoisomers having the E, E or E, Z configuration and within the Formula (I) ##STR1## wherein N is 2-4, A is alkylene or 2 or 3 carbon atoms, R is phenyl or substituted phenyl and R.sup.1 and R.sup.2 are lower alkyl, or, together with the carbon to which attached, form a heterocyclic ring; and pharmaceutically acceptable acid addition salts thereof, a process for their preparation and pharmaceutical compositions comprising the same. The compounds of the general formula (I) can be used in therapy due to their narcosis potentiating, analgesic and antiarrhythmial effect.

2-(phenylmethylene)-1-(diaminoalkoxy) cycloalkanes and their

The invention relates to pharmaceutical compositions possessing valuable antianginal activity. These compositions show higher activity and more favorable therapeutic indices than the reference compound Prenylamine. Preparation of different kinds of pharmaceutical compositions, such as tablets, dragees, capsules and injectable solutions, containing compounds of general formula (I) ##STR1## or their acid addition salts as active ingredients, is disclosed, wherein in formula (I)

Pharmaceutical compositions with antianginal activity

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Budapest, Hungary

Zoltan Budai