Incline Therapeutics, Inc.

Alza Corporation

Morningside Venture Investments Limited

Chrono Therapeutics Inc.

Zita S Netzel

Gary Stacey

Charles Frazer Kilby

Alexander David Norman

Jennifer Darmour

Alan Joel Levy

Congyi Huang

Timothy Charles Frearson

Ling-Kang Tong

David Evans Roth

Kevin W Gelston

Patrick H Ruane

Ronald A Overbeck

Jenny E Hapgood

David R Seward

Bradley E White

Paul G Hayter

John Timothy Lemke

Brian W Read

Corinna X Chen

Michael Nelson

John Lemke

Paul Hayter

A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.

Drug delivery methods and systems

A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.

Method of storing an electrotransport drug delivery device

Iontophoretic drug delivery device

Two-part electrotransport device

Growing community of inventors

Los Altos, CA, United States of America

Zita S Netzel