The Ohio State University

Zilu Wan

James Fuchs

Gireesh Rajashekara

Corey Nislow

Janet Antwi

Anand Kumar

Ulyana Munoz Acuna

Esperanza Carcache De Blanco

Melvin Pascall

Compounds and compositions of matter are provided that are small molecule antimicrobials. The compounds are selected from JH-144, TH-04 or TH-08 or combinations thereof. Compositions of matter are provided which in an embodiment may comprise a carrier, and in further embodiments may comprise a pharmaceutically acceptable excipient, film, biofilm or edible film. Methods of use are provided in which the composition may be administered to a subject in need thereof, and in an embodiment where the subject has a bacterial infection. Other embodiments provide the composition may be contacted with surface to eliminate or reduce bacteria.

Small molecule antimicrobials

Growing community of inventors

Columbus, OH, United States of America

Zilu Wan