Medtronic, Inc.

Duke University

Medtronic Cryocath LP

Medtronic Minimed, Inc.

Zhongping C Yang

Thomas A Anderson

Rick D McVenes

Berthold Stegemann

Todd Jon Sheldon

Subham Ghosh

Andrea Jean Asleson

Wade M Demmer

Michael D Eggen

William J Clemens

Lilian Kornet

Xin Chen

Elizabeth A Mattson

Jian L Cao

Ronald A Drake

Douglas S Hine

Brian P Colin

Jean J Rutten

Becky L Dolan

Jeffrey M Gillberg

James D Reinke

Xiaohong Zhou

Ashutosh Chilkoti

Eric R Williams

Michael William Kimmel

Laurie D Foerster

Kaileigh E Rock

Maurice Ty Verbeek

Shawn M Campbell

Maureen E Lybarger

Kyle R Marquard

Maurice T I Verbeek

Toine Camps

Robert W Stadler

Mark T Stewart

Andrew J Ries

Dan Wittenberger

Jean-Pierre Lalonde

Kenneth C Gardeski

James F Kelley

John D Wahlstrand

Raymond W Usher

Ruth N Klepfer

Nicolas Coulombe

Linnea R Lentz

Vicki L Bjorklund

Nathan A Grenz

Sarah Anne Audet

Alan Cheng

Noelle Christine Hurtig

Alexander R Mattson

Jinho Hyun

Rajiv Shah

Yong Kyun Cho

James Kevin Carney

Matthew David Bonner

Kevin R Seifert

Randal C Schulhauser

Lester O Stener

Tommy Dean Bennett

Terrell M Williams

Anthony W Rorvick

Paul Anthony Iaizzo

Michael Jay Ebert

Gonzalo Martinez

Jay T Rassat

Kathryn Hilpisch

Koen J Michels

Christopher W Storment

Tarek D Haddad

Piotr J Przybyszewski

Ben W Herberg

Kenneth E Cobian

Dina L Williams

Mark A Hjelle

Scott J Brabec

Jean M Carver

Paulus G Adams

Vania Lee

Ven R Manda

Eunjoo Jin

Duane N Mateychuk

Michael L Freiborg

Megan L Platner

Amy Elizabeth Thompson

Lars M Mattison

Genevieve L Gallagher

James M Anderson

Varun Bhatia

Laura Christoferson

Genevieve Louise Eichenberg Gallagher

Kimberly A Ganzel

Derek Young

Noah A Deraney

Christine R Huyett

Jia Yuan Neoh

Devan D Barth

Jorge A Vergen

Clayton P Witherspoon

McKenna Rose Redmond

A medical device is configured to sense a cardiac electrical signal and determine from the cardiac electrical signal at least one of a maximum peak amplitude of a positive slope of the cardiac electrical signal and a maximum peak time interval from a pacing pulse to the maximum peak amplitude. The device is configured to determine a capture type of the pacing pulse based on at least one or both of the maximum peak amplitude and the maximum peak time interval.

His-Purkinje system capture detection

A method of performing bronchial denervation of a bronchus having bronchial nerves along a portion thereof is provided. The method includes providing a cryoablation device having multiple electrodes capable of delivering electrical energy and measuring impedance. At least one bronchial nerve is stimulated with electrical energy. The electrical signals from the at least one bronchial nerve are recorded to provide a first value representative of nerve function. Cryogenic treatment energy is applied to form ice in the bronchus having a thickness to encapsulate the at least one bronchial nerve to cause a reduction in nerve function. The at least one bronchial nerve is restimulated with electrical energy. The electrical signals are recorded from the restimulated at least one bronchial nerve to provide a second value that represents diminished nerve function. The first value and the second value are compared to provide an assessment of the reduction in nerve function.

Method and apparatus for determining bronchial denervation

A pacemaker has a housing and a therapy delivery circuit enclosed by the housing for generating pacing pulses for delivery to a patient's heart. An electrically insulative distal member is coupled directly to the housing and at least one non-tissue piercing cathode electrode is coupled directly to the insulative distal member. A tissue piercing electrode extends away from the housing.

Electrodes for intra-cardiac pacemaker

A method, system and device for implanting an electrode assembly of an implantable medical device in a patient's heart. Positioning one or more radiopaque markers in a coronary sinus of the patient's heart. Positioning, by using the one or more positioned radiopaque markers as a fluoroscopic visual reference, a distal tip of a delivery catheter within a right atrium of the patient's heart so that a distal opening of a lumen of the catheter is against a septal wall of the heart at a location between the ostium of the coronary sinus and the A-V nodal area of the right atrium, and so that the tip of the catheter is generally directed toward a left ventricle of the patient's heart. Advancing the electrode assembly through the lumen of the catheter and into the septal wall.

Implantable medical electrode assemblies, devices, systems, kits, and methods

An implantable medical device configured to deliver pacing therapy, the implantable medical device including a device body configured to position within a heart, where the device body comprises a proximal body portion and a distal body portion and defines a longitudinal axis extending through the proximal body portion and the distal body portion, the proximal body portion is configured to rotate around the longitudinal axis relative to distal body portion, and a leadlet mechanically coupled to the device body, where the leadlet mechanically supports an electrode configured to deliver pacing therapy, and where in response to the proximal body portion rotating relative to the distal body portion, the device body is configured to alter an extension length of the leadlet.

Implantable medical device

In some examples, a system includes a catheter comprising an elongated shaft defining a lumen, and a tether assembly. The tether assembly may include an elongate body, a tether head assembly attached to a distal end of the elongate body, where the tether head assembly includes an attachment mechanism configured to releasably attach to an attachment member of a medical device, and a positioning element fixedly positioned over the elongate body and configured to align the attachment mechanism with the attachment member when the tether head assembly is extended distally out of the lumen. The positioning element may include a distal end, a proximal end, and a length between the distal end and proximal end that is less than a length of the elongate body. The tether head assembly, elongate body, and positioning element may be movable within the lumen of the elongated shaft.

Tether assemblies for medical device retrieval systems

A medical device having an elongate body with a proximal portion, a distal portion, and defining a lumen therethrough. The medical device has an expandable element coupled to the distal portion of the elongate body, the expandable element defining a proximal portion, a distal portion opposite the proximal portion and an intermediate portion disposed between the proximal portion and the distal portion. The expandable element also has an inner surface and an outer surface opposite the inner surface. The medical device has a plurality of cutting members, each cutting member being coupled with the outer surface of the expandable element, each cutting member having a proximal end and a distal end opposite the proximal end, the proximal end being proximate the proximal portion of the expandable element and the distal end being proximate to the intermediate portion of the expandable element.

Interatrial septoplasty cutting device

An example device includes an elongated housing, a first and second electrode, and signal generation circuitry. The housing can be implanted within a single first chamber of the heart. The first electrode extends distally from the distal end of the elongated housing. A distal end of the first electrode can penetrate into wall tissue of a second chamber of the heart. The second electrode, extending from the distal end of the elongated housing, is configured to flexibly maintain contact with the wall tissue of the first chamber without penetration of the wall tissue of the first chamber by the second electrode. Signal generation circuitry can be within the elongated housing and coupled to the first and second electrode. The signal generation circuitry can deliver cardiac pacing to the second chamber via the first electrode and the first chamber via the second electrode.

Electrode configuration for a medical device

A method of delivering a pacing lead may include locating a potential implantation site adjacent to or within the triangle of Koch region of a patient's heart. The method may include advancing a pacing lead to the potential implantation site. The pacing lead has an elongate body and a fixation element coupled to a distal portion and attachable to the right-atrial endocardium adjacent to or within the triangle of Koch region. The method may include implanting the pacing lead at the potential implantation site to or sense electrical activity of the left ventricle in the basal and/or septal region of the left ventricular myocardium of the patient's heart. The pacing lead may include a lumen configured to receive a guide wire. A sheath of a delivery system used to deliver the pacing lead may include two or more curves to facilitate implanting the pacing lead at the implantation site.

Delivery systems and methods for left ventricular pacing

A method for performing bronchial denervation, the method comprising an electromyography system having a cryoablation device with at least two recording electrodes. The electromyography system being configured to calculate a difference between a first electromyogram signal received from the first recording electrode and a second electromyogram signal received from the second recording electrode to generate a recorded electromyogram and compare the recorded electromyogram to a reference electromyogram.

Apparatus and method for targeted bronchial denervation by cryo-ablation

A surgical method treats infections on a lead positioned at least partially within a patient's body. The surgical method includes uncoupling the lead from a pulse generator. The lead is then coupled to an ultrasound wave generator. Ultrasound waves are propagated from the ultrasound wave generator through the lead. Systems are disclosed.

Surgical system and methods

A medical device includes a motion sensor for producing a motion signal including cardiac event signals. The medical device generates a ventricular pacing pulse upon expiration of a pacing interval. The medical device determines a synchrony metric from the motion signal after a delivered ventricular pacing pulse and adjusts the pacing interval based on the synchrony metric.

Medical device and method for controlling pacing interval to promote mechanical heart chamber synchrony

An implantable lead system may include an adjustable lead assembly. The lead assembly may include a fixation member and an implantable lead slidably coupled to and rotatable relative to the fixation member. The implantable lead system may include a telescoping delivery system. The delivery system may include an outer catheter and an inner catheter slidably coupled to and rotatable relative to the outer catheter. The lead assembly may be implanted in a cardiac septal wall through the delivery assembly.

Adjustable lead systems for cardiac septal wall implantation

An implantable medical device system receives a cardiac electrical signal produced by a patient's heart and comprising atrial P-waves and delivers a His bundle pacing pulse to the patient's heart via a His pacing electrode vector. The system determines a timing of a sensed atrial P-wave relative to the His bundle pacing pulse and determines a type of capture of the His bundle pacing pulse in response to the determined timing of the atrial P-wave.

Implantable medical device and method for determining his bundle pacing capture

An implantable medical device (IMD) comprises a plurality of deep tines configured to be advanced into a septum of a heart of a patient in different directions that are not parallel to a longitudinal axis of the implantable medical device, wherein each deep tine of the plurality of deep tines is configured to deliver cardiac pacing to cardiac tissue distal to a chamber of the heart in which the IMD is implanted, and one or more shallow electrodes engageable with the septum, wherein the one or more shallow electrodes are configured to deliver cardiac pacing to the chamber of the heart in which the IMD is implanted.

Multi-electrode implantable medical device (IMD)

Growing community of inventors

Woodbury, MN, United States of America

Zhongping C Yang