Peking University

Boe Technology Group Co., Ltd.

Yantai Dongcheng Biochemicals Co., Ltd

Zhongjun Li

Long Wang

Xiangbao Meng

Yu Chen

Liye Duan

Feng Jiang

Xiao Zhang

Xiaoming Wu

Qingbao Yang

Jiliang Wang

Shan Liu

Siwang Yu

Li Zhou

Tian He

Jianqiang Wang

Linling Que

Dongbo Lu

Huiying Liu

Meiqi Zhang

Wang Yao

Jiexing Zhong

A fucosylated chondroitin sulfate oligosaccharide having the structure as shown in J, and further disclosed is a method for preparing the fucosylated chondroitin sulfate oligosaccharide: using a chondroitin sulfate A salt as a raw material, sequentially performing enzymolysis, a group protection operation, and glycosylation to synthesize the oligosaccharide compound; the certainty of the described structure allows said oligosaccharide to be applied to the medical field.

Oligosaccharide, preparation method therefor, composition thereof and use thereof

This invention discloses the use of aza-tryptanthrin derivatives as an IDO1 and/or TDO inhibitors, and the derivatives are represented by the general Formula (I). The compounds represented by the Formula (I) have inhibitory effects on indoleamine-2,3-dioxygenase 1 (IDO1) and/or tryptophan-2,3-dioxygenase (TDO), and can be used for treating diseases having the pathological features of IDO1 and/or TDO-mediated tryptophan metabolism, including but not limited to tumors, autoimmune disease, infectious diseases, Alzheimer's disease, depression, anxiety. 

Use of aza-tryptanthrin derivatives as inhibitors of IDO1 and/or TDO

The present disclosure provides an active matrix organic light-emitting diode array substrate comprising: a substrate; a plurality of pixel units located on the substrate and arranged in an array, each of the plurality of pixel units comprising a thin film transistor, an organic light-emitting diode and a bottom plate of a storage capacitor; a pixel definition layer spacing apart two adjacent pixel units from each other; and a top plate of the storage capacitor provided on the pixel definition layer, the top plate of the storage capacitor being spaced apart from the bottom plate of the storage capacitor by the pixel definition layer. The bottom plate is arranged above a gate electrode of the thin film transistor and electrically connected to the gate electrode of the thin film transistor.

AMOLED array substrate, producing method thereof and display apparatus

Provided is a fused acridine derivative as formula (I), which has good antitumor activity. In addition, also provided are a process for preparing the derivative, a pharmaceutical composition containing the derivative, and the use thereof. 

Fused acridine derivative and pharmaceutical composition, preparation method and use thereof

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Beijing, China

Zhongjun Li