Suzhou Rainmed Medical Technology Co., Ltd.

Zhiyuan Wang

Guangzhi Liu

Lin Chen

Yunfei Huo

Wei Dai

Xingyun Wu

Wenbin Cao

Yanjun Gong

Tieci Yi

Jianping Li

Xinyu Wu

Bo Zheng

Yong Huo

The present disclosure provides a method for correcting a resting blood flow velocity on the basis of an interval time between angiogram images, comprising: acquiring, in an angiography state, an average blood flow velocity Vfrom a coronary artery inlet to a distal end of a coronary artery stenosis (S); acquiring a time difference Δt between start times of two adjacent bolus injections of contrast agent (S); obtaining a correction coefficient K according to the time difference Δt (S); obtaining a resting blood flow velocity Vaccording to the correction coefficient K and the average blood flow velocity V(S), as well as an apparatus configured for implementing the above method. The disclosure obtains the resting blood flow velocity Vaccording to the correction coefficient K and the average blood flow velocity V.

Method and apparatus for correcting blood flow velocity on the basis of interval time between angiogram images

The present disclosure provides a method and an apparatus for acquiring a contour line of a blood vessel according to a centerline of the blood vessel. The method comprises: extracting a centerline of a blood vessel according to a two-dimensional coronary artery angiogram image (S); obtaining an image of a straightened blood vessel according to the centerline of the blood vessel (S); setting a threshold Dfor a diameter of the blood vessel on the image of the straightened blood vessel (S); generating a preset contour line of the blood vessel on both sides of a centerline of the straightened blood vessel according to the D(S); making the preset contour line of the blood vessel step-by-step approach the centerline of the straightened blood vessel to acquire a contour line of the straightened blood vessel (S); projecting the contour line of the straightened blood vessel back onto the image of the centerline of the blood vessel to obtain a contour line of the blood vessel (S).

Method and apparatus for acquiring contour line of blood vessel according to centerline of blood vessel

A method for calculating coronary artery fractional flow reserve includes determining myocardial volume by extracting myocardial images; locating a coronary artery inlet and accurately segmenting coronary arteries; generating a grid model required for calculation by edge detection of coronary artery volume data; determining myocardial blood flow in a rest state and CFR by non-invasive measurement; calculating the total flow at the coronary artery inlet in a maximum hyperemia state; determining the flow in different blood vessels in the coronary artery tree in the maximum hyperemia state and then determining flow velocity Vin the maximum hyperemia state; using Vas the flow velocity at the coronary artery inlet and calculating a pressure drop ΔP from the coronary artery inlet to a distal end of a coronary stenosis, and a mean intracoronary pressure Pd at the distal end of the stenosis P=P−ΔP, and calculating fractional flow reserve.

Method for calculating coronary artery fractional flow reserve on basis of myocardial blood flow and CT images

A method for calculating an index of microcirculatory resistance includes determining myocardial volume by extracting myocardial images; locating a coronary artery inlet and accurately segmenting coronary arteries; generating a grid model required for calculation; determining myocardial blood flow in a rest state and CFR; calculating total flow at the coronary artery inlet in a maximum hyperemia state; determining flow in different blood vessels in a coronary artery tree in the maximum hyperemia state and then determining a flow velocity Vin the maximum hyperemia state; obtaining the average conduction time in the maximum hyperemia state Tmn, and calculating a pressure drop ΔP from the coronary artery inlet to a distal end of a coronary artery stenosis, and a mean intracoronary pressure Pat the distal end of the stenosis P=P−ΔP, and calculating the index of microcirculatory resistance.

Method for calculating index of microcirculatory resistance based on myocardial blood flow and CT image

A method, device and system for calculating a microcirculation indicator are provided. A method includes: injecting a vasodilator and subjecting a blood vessel to be measured to coronary angiography; selecting at least one angiographic image of a first body position when the blood vessel to be measured is in a resting state and an angiographic image of a second body position when the blood vessel to be measured is in a dilated state; obtaining a three-dimensional coronary artery vascular model by three-dimensional modeling; injecting a contrast agent, and obtaining time Ttaken for the contrast agent flowing from an inlet to an outlet of the segment of blood vessel and time Ttaken for the contrast agent flowing from an inlet to an outlet of the segment of blood vessel; obtaining the microcirculation indicator.

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Suzhou, China

Zhiyuan Wang