Columbia University

Beijing Bytedance Network Technology Co., Ltd.

Zhixing Chen

Wei Min

Lu Wei

Fanghao Hu

Yihui Shen

Exemplary methods, systems and computer-accessible medium for detecting at least one condition of at least one disease. In particular, it is possible to administer at least one composition to at least one patient, where the at least one composition includes at least one bond-edited compound configured to target at least one of a disease tissue or a pathogen. Further, it is possible to receive information related to the administration of the composition to the patient. It is also possible to detect the at least one bond-edited compound using a Raman scattering arrangement.

Devices, compositions and methods for imaging with Raman scattering

Methods, systems and computer-accessible medium for imaging a living cell or a living organism with bond-edited compounds using stimulated Raman scattering are disclosed. The method comprises the steps of introducing one or more bond-edited compounds into a live cell or a living organism, and detecting a vibrational tag in the cell or organism with stimulated Raman scattering. Also disclosed are methods for detecting a disease condition in a subject, methods for monitoring treatment for a disease condition, methods for screening an agent, methods for tracing a cellular process in a live cell using bond-edited compounds in combination with stimulated Raman scattering. Also disclosed are a composition for labeling a target cell with at least one bond-edited compound and devices for imaging bond-edited compounds by stimulated Raman scattering.

Devices, compositions and methods for imaging with raman scattering

Techniques for reconstructing three-dimensional face images are described herein. The disclosed techniques include acquiring a real two-dimensional face key point and a predicted two-dimensional face key point; solving a first loss function consisting of the real two-dimensional face key point, the predicted two-dimensional face key point and a preset additional regular constraint term to iteratively optimize an expression coefficient, where the additional regular constraint term is used for constraining the expression coefficient such that the expression coefficient represents a real state of a face; and reconstructing a three-dimensional face image based on the expression coefficient.

Growing community of inventors

Beijing, China

Zhixing Chen