Apple Inc.

Beigene, Ltd.

Beigene Switzerland Gmbh

Beone Medicines I Gmbh

International Business Machines Corporation

Hoffmann-la Roche Inc.

China Three Gorges Corporation

F. Hoffmann-la Roche Ag

Guangxi University

Zhiwei Wang

Yunhang Guo

Yaoqi Yan

Dawei Zhang

Qiang Miao

Lijie Zhang

Longda Xing

Fangli Xu

Srinivasan Nimmala

Srirang Ashok Lovlekar

Yuqin Chen

Sethuraman Gurumoorthy

Murtaza A Shikari

Sree Ram Kodali

Jing Li

Muthukumaran Dhanapal

Gongyin Shi

Lele Cui

Haijing Hu

Huarui Liang

Jing Wang

Vijay Venkataraman

Changyou Zhou

Hexiang Wang

Lai Wang

Haibo Zhao

Sanjia Xu

Junzhen Qin

Beibei Wang

Deepankar Bhattacharjee

Guoliang Zhang

Bo Ren

Kexin Ma

Alex Yee Kit Ho

Shangfeng Li

Hai Xue

Jishan Gao

Wen Zhao

Lakshmi N Kavuri

Madhusudan Chaudhary

Qin Zhang

Chengrong Qin

Umesh K Shukla

Shuangfei Wang

Wenping Lou

Tao Xie

Yong Zhong

Ling Peng

Bo Wang

Desheng Yu

Hanzi Sun

Jian Zhang

Li Ni Zhang

Li Su

Hao Sun

Krisztian Kiss

Feng Zhang

Jianxiong Shi

Matthias Heinrich Nettekoven

Farouk Belghoul

Tong Zhang

Mark Rogers-Evans

Uwe Grether

Stephan Roever

Paul Hebeisen

Caterina Bissantz

Tanja Schulz-Gasch

Nan Hu

Kang Li

Jie Yu

Srinivas Burugupalli

Jun He

Bing Hua Zhao

Atsushi Kimbara

Li Xu

Jing Song

Christoph Ullmer

Min Wei

David Boettger

Chao Gao

Marco Prunotto

Hailong Yang

Yun Gao

Yu Wu

Lusong Luo

Qingping Liu

Peng Gan

Shanshan Zhao

An Chan

Yantong Dong

Wulun Yang

Lina Gu

Aiman J Sang

Ying Zhang

Qian Sun

Jiqi Pan

Wanli Wu

Jingyang Lu

Disclosed are methods, systems, and computer-readable medium to perform operations including: receiving, from an application layer of a user equipment (UE), a first uplink packet at a first time; identifying a latency between the first time and a first instance of a periodic transmission resource during which the first uplink packet is transmitted by the UE; and providing information indicative of the latency to the application layer of the UE.

Reduction of latency in wireless communication systems

Disclosed herein is a tricyclic compound of Formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising thereof. Also disclosed is a method of treating HPK1 related disorders or diseases by using the compound disclosed herein.

Tricyclic compounds as HPK1 inhibitor and the use thereof

Disclosed herein is a compound of Formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising thereof. Also disclosed is a method of treating HPK1 related disorders or diseases by using the compound disclosed herein.

Pyrrolo[2,3-b]pyrazines as HPK1 inhibitor and the use thereof

Disclosed herein are cyclic di-nucleotide compounds and derivatives thereof that may be useful as STING agonists, and a pharmaceutical composition comprising the same. Also disclosed herein is the process for synthesis and to uses of such cyclic di-nucleotide compounds in various diseases including cancer, HIV infection and HBV infection.

Cyclic dinucleotides as sting agonists

An electronic device receives an indication of a number of physical resource blocks and subcarrier spacing of at least a portion of a transmission channel and determines a dynamic transmission bandwidth, or receives an indication of a modulation coding scheme of the transmission channel and determines a modulation order. The electronic device transmits, using a transmitter, a signal over at least the portion of the transmission channel based on the dynamic transmission bandwidth being less than or equal to a threshold bandwidth, or the modulation order not corresponding to an additional power backoff, using a first power based on a maximum output power capacity of the electronic device and a maximum power reduction. Otherwise, the electronic device transmits the signal over at least the portion of the transmission channel at a second power based on the maximum output power capacity, the maximum power reduction and the additional power backoff.

Dynamic transmission power backoff

Devices and associated methods for operating a dual-subscriber identity module (SIM) dual-standby (DSDS) user equipment device (UE) configured with a first SIM and a second SIM. The UE performs communications with a first cellular network using the first SIM and a first radio resource control (RRC) connection, and receives a request to perform a higher priority communication using the second SIM. In response to the request to perform the higher priority communication, the UE transmits a request to the first network to suspend the first RRC connection. After transmission of the request to suspend the first RRC connection, the UE receives a message from the first network to place the first RRC connection in an inactive state, and initiates a timer, wherein the timer is used to determine whether the first RRC connection remains in the inactive state or transitions to an idle state.

User equipment having multiple subscriber identity modules with improved suspend / resume operation

A user equipment (UE) includes a first subscriber identification module (SIM) and a second SIM. The UE is configured to establish a first cellular network connection based on, at least, the first SIM and a second cellular network connection based on, at least, the second SIM. The UE detects a collision between i) multiple paging occasions or ii) multiple paging frames. The UE then initiates a procedure for updating a paging occasion for the first cellular network connection. The UE monitors for a page over the first cellular network connection during the paging occasion.

Adjust paging occasion to resolve paging collision at a multi-SIM device

Aspects are described for a user equipment (UE) comprising a transceiver configured to enable wireless communication with a base station; and a processor communicatively coupled to the transceiver. The processor is configured to receive a sounding reference signal (SRS) resource configuration from the base station, wherein the SRS resource configuration indicates at least a first SRS resource and a second SRS resource. The processor is further configured to transmit a first SRS via the first SRS resource to the base station using a first antenna coupled to the transceiver and transmit a second SRS via the second SRS resource to the base station using a second antenna coupled to the transceiver. The processor is further configured to receive an SRS resource indicator (SRI) from the base station based on at least one of the transmission of the first SRS or the second SRS; select the first antenna based on the SRI indicating the first SRS resource; and transmit uplink data to the base station using the first antenna.

Method of codebook sounding reference signal (SRS) antenna mapping to improve uplink performance

Disclosed herein is a compound of Formula (I) for inhibiting both Bcl-2 wild type and mutated Bcl-2, in particular, Bcl-2 G101V and D103Y, and a method of using the compound disclosed herein for treating dysregulated apoptotic diseases.

Bcl-2 inhibitor

Systems, methods, and apparatuses disclosed herein can compensate for imbalances between multiple transport streams of an uplink (UL)-multiple-input and multiple-output (MIMO) transmission. These systems, methods, and apparatuses can adjust one or more signal metrics of multiple recovered transport streams of the UL-MIMO transmission that are received in the presence of imbalances between the multiple transport streams of the UL-MIMO transmission. As an example, these systems, methods, and apparatuses can inject noise into one or more of the multiple recovered transport streams to adjust the one or more signal metrics of the multiple recovered transmission streams to lessen the imbalances between the multiple transmission streams.

Imbalance compensation for uplink (UL)—multiple-input and multiple-output (MIMO) transmissions

This disclosure relates to techniques for multi-RAT and DSDA capable wireless devices to handle frame blanking in a wireless communication system. A wireless device may establish wireless links according to a first radio access technology and a second radio access technology. The wireless device may determine to perform transmit and receive blanking for one or more antennas of the wireless device for the first radio access technology to perform sounding reference signal transmissions for the second radio access technology based at least in part on a band combination for the wireless links. The wireless device may determine a modification to channel state feedback reporting for the first radio access technology based at least in part on the transmit and receive blanking. The wireless device may perform channel state feedback reporting using the determined modification.

Handling transmit and receive blanking for multi-RAT and DSDA capable wireless devices

Disclosed herein is 3-[(1H-pyrazol-4-yl)oxy]pyrazin-2-amine compounds of Formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising thereof. Also disclosed is a method of modulating, e.g., inhibiting or treating HPK1 related disorders or diseases including cancer by using the compound disclosed herein

3-[(1H-pyrazol-r-yl)oxy]pyrazin-2-amine compounds as HPK1 inhibitor and use thereof

A gap caulking device and a caulking method are provided, wherein the gap caulking device includes long plates, short plates, a dial plate, a three-way joint, a tensioner and a limit rod, and a closed quadrilateral structure with an adjustable angle is formed by two long plates hinged to each other and two short plates hinged to each other, a dial plate and a pointer are respectively provided on the two short plates, damping rods hinged on the two short plates to each other and a three-way joint matched with the two long plates are passed through by a limit rod to achieve connection limiting, and a shape memory alloy wire is connected to the three-way joint by a tensioner and is parallel to the limit rod. The problem is overcome that the original traditional wedge-shaped material that gaps rely on has a single filling function.

Gap caulking device and a caulking method

The present invention relates to a crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetr a-hydropyrazolo[1,5-a]pyrimi dine-3-carboxamide for inhibiting Btk, methods of preparation thereof and pharmaceutical compositions, and use of the crystalline form above in the treatment of a disease, or in the manufacturing of a medicament for the treatment of a disease.

Crystalline form of (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof

Growing community of inventors

Beijing, China

Zhiwei Wang