Shanghai Microport Medical (group) Co., Ltd.

Forqaly Medical (shanghai) Co., Ltd.

Zhirong Tang

Qiyi Luo

Yan Li

Jie Zhang

Peng Huang

Xu Cai

Yu Li

Junfei Li

Chengyun Yue

Bo Yi

Changchun Wang

Changsheng Wu

Dadong Zhang

Xi Hu

Zhaohua Chang

Dawei Wang

Zhiyong Xie

Yan Hu

Jianjun Li

Sen Wang

Qiwen Zheng

Buzhong Zheng

Chengjun Le

Xia Hao

The present invention discloses a flexible shaft structure insulating wear particles by perfusion, which includes a flexible transmission shaft, a proximal holder is provided at one end of the flexible transmission shaft, a distal holder is provided at the other end of the flexible transmission shaft, a constraint insulator and an outer sheath tube are provided outside the flexible transmission shaft, and the constraint insulator sequentially includes an inner constraint layer, an insulation layer and an outer constraint layer from inside to outside; a perfusion inflow annular cavity is formed between the outer constraint layer and the outer sheath tube and between the outer constraint layer and the insulation layer, respectively, and a static sealed inner cavity is formed between the inner constraint layer and the insulation layer and between the inner constraint layer and the flexible transmission shaft, respectively; the proximal holder is provided with a perfusion inlet pipeline communicated with the perfusion inflow annular cavity and a perfusion exhaust pipeline communicated with the static sealed inner cavity; and the distal holder is provided with a perfusion insulation cavity. According to the present invention, the generated wear particles can be effectively insulated, the stability and consistency of perfusion flow of the product are improved, and the problems of vibration and noise of the flexible shaft under high-speed rotation are solved.

Flexible shaft structure insulating wear particles by perfusion

An interventional medical device and manufacturing method thereof. The interventional medical device comprises: a stent body (); a surface of the stent body () being provided with a drug releasing structure (), and drug in the drug releasing structure () being drug for suppressing proliferation of adventitial fibroblasts and a drug for suppressing proliferation of intimal and/or smooth muscle cells. In use, after interventional medical device is implanted into a human body, the drug for suppressing proliferation of adventitial fibroblasts carried thereon can promote the compensatory expansion of the vessel, and the drug for suppressing proliferation of intimal cells and/or smooth muscle cells carried thereon can suppress intimal proliferation of the vessel. The combination of the two kinds of drugs greatly reduces the occurrence rate of in-stent restenosis.

Interventional medical device and manufacturing method thereof

A method for loading a medical appliance with a medicament and/or a polymer is disclosed, the medical appliance comprising one or more grooves or holes loaded with the medicament and/or polymer. The method comprising the steps of: 1) capturing an image of the grooves or holes of the medical appliance, wherein the image contains at least one complete pattern of the grooves or holes; 2) performing digital image processing on the captured image to obtain the pattern of the grooves or holes; 3) calculating a central position of the pattern of the grooves or holes, and determining an actual central position of the grooves or holes based on the central position; 4) adjusting a relative position of a loading device to the medical appliance to align an outlet of the loading device with the actual central position of the grooves or holes; and 5) opening the outlet of the loading device to load the grooves or holes. A device for loading a medical appliance with a medicament and/or a polymer is further disclosed.

Method and device for loading medical appliance with drugs and/or polymers

A stent for a bifurcated vessel includes a stent body () with two open ends (). The stent body () includes multiple sets of annular units () having multiple undulating rods () and connecting rods () positioned between adjacent annular units () and used to connect the adjacent annular units (). At least one open end () of the stent body () has a slope structure.

Stent for bifurcated vessel

The present invention discloses an interventional medical device and methods of making the same. At least one coating layer is disposed on the outer surface of the interventional medical device and the material of the outmost layer of the coating layer is a sulfonate group-containing polymer. In the present invention, the material of the outmost layer of the interventional medical device is a sulfonate group-containing polymer. The polymer is endowed with a same surface property as that of heparin in addition to appropriate hydrophilicity due to the presence of the sulfonate group. After the interventional medical device is implanted into the human body, a hydrophilic surface is formed on the outer surface of the interventional medical device which is also negatively charged in the body fluid. Therefore, cells can easily adhere and grow on the outer surface thereof as a result of the enhanced cell compatibility. Furthermore, due to a surface property that is the same as that of heparin, the material is provided with excellent anticoagulant properties which inhibit the thrombosis and lower down the incidence rate of post-operational complications.

Intervention medical device and preparation thereof

A method and a device for loading a medical appliance with a medicament and/or polymer includes capturing images of a plurality of grooves or holes of the medical appliance using an image capturing device; performing digital image processing on the image of each of the grooves or holes to obtain a pattern of each of the grooves or holes; calculating a central position of the pattern of each of the grooves or holes, and determining a loading position of each of the grooves or holes based on the central position; and adjusting a relative position between a loading device and the medical appliance to align an outlet of the loading device with the loading position of the medical appliance, and loading each of the grooves or holes with the medicament and/or polymer. The method and device can load the medical appliance with the medicament and/or polymer fast and efficiently.

Method and device for loading medical appliance with medicaments and/or polymers

The present invention discloses a coronary artery vascular stent with drug carrying slots (), comprising a plurality of main supporting unit rings () and connecting rods (). Said main supporting unit rings comprise a plurality of unit waves. There are drug carrying slots () at the outer surface of the rods of said unit waves, characterized in that the total slot length of the drug carrying slots () is 60%-75% of the total wave rod length of the main supporting unit rings ().

Coronary artery vascular stent with medicine carrying slots

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Shanghai, China

Zhirong Tang