Bgi-Shenzhen Co., Limited

Bgi Shenzhen

Bgi Agricultural and Circular Economic Tech Co., Ltd.

Zhilong Lin

Jie Liu

Bo Wen

Chao Peng

Ting Tong

Fen Mo

Qiong Shi

Chaoqin Du

Disclosed are a conotoxin polypeptide &#x3ba;-CPTx-bt105, a method for preparation thereof, and an application thereof. The conotoxin polypeptide of the present invention consists of 16 amino acids, has a molecular weight of 1626.62 daltons, and has the full sequence GICCVDDTCTTHSGCL (SEQ. ID NO. 1).

Conotoxin polypeptide &#x3ba;-CPTx-bt105, and method for preparation thereof and application thereof

Disclosed are a conotoxin polypeptide &#x3ba;-CPTx-bt102, a method for preparation thereof, and an application thereof. The conotoxin polypeptide of the present invention consists of 15 amino acids, has a molecular weight of 1660.61 daltons, and has the full sequence RCRCEQTCGTCVPCC (SEQ. ID NO. 1).

Conotoxin polypeptide K-CPTX-BT102, and method for preparation thereof and application thereof

Disclosed are a conotoxin polypeptide &#x3ba;-CPTx-bt103, a method for preparation thereof, and an application thereof. The conotoxin polypeptide of the present invention consists of 29 amino acids, has a molecular weight of 3141.43 daltons, and has the full sequence RTNCGETCLKDEQCVGACQICVPSQLKCL (SEQ ID NO. 1).

Conotoxin polypeptide &#x3ba;-CPTx-bt103, and method for preparation thereof and application thereof

Disclosed are a conotoxin polypeptide &#x3ba;-CPTx-bt104, a method for preparation thereof, and an application thereof. The conotoxin polypeptide of the present invention consists of 11 amino acids, has a molecular weight of 1313.47 daltons, and has the full sequence SLCCPEDRWCC (SEQ. ID NO. 1).

Conotoxin polypeptide &#x3ba;-CPTx-bt104, and method for preparation thereof and application thereof

Provided are a conotoxin peptide &#x3ba;-CPTx-bt103 and a derivative polypeptide. The amino acid sequence of the conotoxin peptide is indicated by SEQ ID NO: 1. Also provided are a conotoxin peptide preparation method and uses of the conotoxin peptide in the treatment of diseases related to a calcium ion channel.

Conotoxin peptide &#x3ba;-CPTx-btl03, preparation method therefor, and uses thereof

Provided is a new conotoxin peptide &#x3ba;-CPTx-bt101. The conotoxin peptide &#x3ba;-CPTx-bt101 has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1, or has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1 and that is formed after substitution, addition or deletion of one or more amino acids are performed and has original functions. Also provided is polynucleotide for coding the peptide, comprising a constructed body of the polynucleotide, an expression carrier and transformed cells. A peptide preparation method and uses in the treatment of diseases related to a calcium ion channel.

Conotoxin peptide &#x3ba;-CPTx-BTL01, preparation method therefor, and uses thereof

Provided is a new conotoxin peptide &#x3ba;-CPTx-btl02. The conotoxin peptide &#x3ba;-CPTx-btl02 has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1, or has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1 and that is formed after substitution, addition or deletion of one or more amino acids are performed and has original functions. Also provided is polynucleotide for coding the peptide, comprising a constructed body of the polynucleotide, an expression carrier and transformed cells. A peptide preparation method and uses in the treatment of diseases related to a calcium ion channel.

Conotoxin peptide &#x3ba;-CPTX-BTL02, preparation method therefor, and uses thereof

Provided are a conotoxin peptide &#x3ba;-CPTx-btl04 and a derivative polypeptide. The amino acid sequence of the conotoxin peptide is indicated by SEQ ID NO: 1. Also provided are a conotoxin peptide preparation method and uses of the conotoxin peptide in the treatment of diseases related to a calcium ion channel.

Conotoxin peptide &#x3ba;-CPTX-BTL04, preparation method therefor, and uses thereof

Disclosed are a conotoxin polypeptide &#x3ba;-CPTx-bt101, a method for preparation thereof, and an application thereof. The conotoxin polypeptide of the present invention consists of 18 amino acids, has a molecular weight of 1872.72 daltons, and has the full sequence KCCTMSVCQPPPVCTCCA (SEQ. ID NO. 1).

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Guangdong, China

Zhilong Lin