Shanghai Longwood Biopharmaceuticals Co., Ltd.

Dell Products Inc.

Zhihong Zeng

Zhe Wang

Min Liu

Yongsheng Guo

Yubing Zhang

Sai Yang

Mengze Liao

Xiaoguang Wang

Guoqin Fan

Meng Zhou

Rongzhen Jiang

Embodiments of the present disclosure relate to a method, an electronic device, and a computer program product for system feature management. The method for system feature management provided by the embodiments of the present disclosure includes loading a feature item set including multiple feature items, where the multiple feature items respectively correspond to multiple microservices, the feature items each include at least an availability indicator and a status indicator, the availability indicator indicates whether the feature item is available, and the status indicator indicates whether the feature item is enabled while the feature item is available; and disabling a first feature item in the feature item set in response to an availability indicator of the first feature item indicating that the first feature item is unavailable. In this way, software can be made to better adapt to more platforms. Moreover, a user can choose to enable or disable some services as required, thereby reducing energy consumption.

Method, electronic device, and computer program product for system feature management

Embodiments of the present disclosure relate to a method, an electronic device, and a computer program product for request controlling. The method includes determining, in response to receiving a request for computing resources, a first control window including a plurality of control time slots, the request being received in a receive time slot of the plurality of control time slots. The method further includes determining a quantity of available computing resources within the first control window according to a position of the receive time slot in the plurality of control time slots. The method further includes processing the request within the first control window if the quantity of available computing resources does not exceed a threshold. The method can improve the capability of controlling requests for computing resources, and reduce congestion caused by a large number of requests exceeding the load of computing resources.

Method, electronic device, and computer program product for request controlling

Provided is a selective JAK kinase selective inhibitor and a preparation method and the use thereof. In particular, provided is a compound having the structure as shown in chemical formula (I) as a JAK kinase inhibitor or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt, a hydrate or a solvate thereof. 

JAK kinase inhibitor and preparation method and use thereof

Provided in the present application are a sulfonyl amidine as represented by formula (I) as an indoleamine-2,3-dioxygenase inhibitor, and a preparation method therefor and the use thereof. The compound of formula (I) in the present application can be used as an indoleamine-2,3-dioxygenase inhibitor in the preparation of a drug for preventing and/or treating indoleamine-2,3-dioxygenase-mediated diseases. 

Sulfonyl amidine as indoleamine-2,3-dioxygenase inhibitor, and preparation method therefor and use thereof

The present invention relates to an MDM2 inhabitor, a preparation method therefor, a pharmaceutical composition thereof, and the use thereof specifically, the present invention relates to a compound represented by formula I. The compound has excellent MDM2 inhibitory activities, and can be used for preparing a pharmaceutical composition for treating cancers and other diseases related to MDM2 activities, particularly p53 wild-type cancer. 

MDM2 inhibitor, preparation method therefor, pharmaceutical composition thereof and use thereof

Disclosed are an endocyclic thiamidinoamide-arylamide compound and a pharmaceutical composition comprising the compound described above, and the use of the compound or pharmaceutical composition in the treatment of hepatitis B. In particular, disclosed is a compound that can be used as an HBV replication inhibitor and has the structure as shown in chemical formula (L), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt, hydrate or solvate thereof. 

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Shanghai, China

Zhihong Zeng