Chinese Academy of Sciences

State Grid Corporation of China

Chinese Academy of Medical Sciences

North China Electric Power University

State Grid Tianjin Electric Power Company

China Electric Power Research Institute Company Limited

State Grid Beijing Electric Power Company

Institute of Medical Support Technology, Academy of System Engineering, Academy of Military Science

Tiangong University

Institute of Medical Support Technology of Academy of System Engineering of Academy of Military Science

Zhihong Li

Jing Li

Zhihui Zhang

Hailin Qin

Anjun Deng

Lianqiu Wu

Jing Wang

Ye Li

Jian Yang

Li Song

Xiaohui Wang

Wenjie Wang

Feng Tian

Lei Dong

Liqiang Zhao

Tianjiao Pu

Jiancheng Yu

Renle Huang

Xianjun Ge

Chunlai Wang

Minghao Ai

Fumin Qu

Jing Guan

Jinqian Yu

Haijing Zhang

Huachen Song

Xiaonan Tang

Sheng Ding

Jimin Wu

Naishi Chen

Shujie Huang

Miaolei Jing

Xuexin Chu

An 8-dihalomethyl berberine-type quaternary ammonium salt compound represented by general formula (I) or (II) and an application thereof in preparing a drug. The compound shows hydrophilicity and has antimicrobial, anti-inflammatory, anti-ulcerative colitis, and antitumor activities, while having no or low toxicity.

Hydrophilic berberine-type derivative and application thereof in preparing drug

The present invention relates to an alkyl chitosan-graphene oxide composite sponge and preparation method and application thereof. The alkyl chitosan-graphene oxide composite sponge provided by the present invention includes alkyl chitosan and graphene oxide absorbed on the alkyl chitosan, and the adsorbing capacity of the graphene oxide is 3-28 wt. %. In the present invention, alkyl chitosan is used as a matrix to combine graphene oxide and alkyl chitosan; the obtained composite sponge has excellent hemostatic performance and blood absorption capacity. Results of embodiments indicate that the in-vitro whole blood coagulation time is less than 58 s, the hemostasis time of a rabbit femoral artery hemorrhage model is less than 155 s, the hemorrhage mass is less than 5.4 g, and the hemostatic effect is superior to a pure alkyl chitosan sponge or graphene oxide powder when the composite sponge provided by the present invention is used for hemostasis.

Alkyl chitosan-graphene oxide composite sponge and preparation method and application thereof

An active power distribution network multi-time scale coordinated optimization scheduling method and storage medium are provided. The method includes the following steps: performing long-time scale optimization scheduling of an active power distribution network; performing short-time scale rolling optimization scheduling on the basis of MPC of the active power distribution network according to an optimization result of the long-time scale optimization scheduling of the active power distribution network. By using a model prediction control method, taking the long-time scale optimization scheduling result as a reference, and performing short-time scale rolling correction, the optimization scheduling of the active power distribution network is achieved, thereby reducing unfavorable influences of prediction precision of a distributed power supply and a low-voltage load on the optimization scheduling.

Active power distribution network multi-time scale coordinated optimization scheduling method and storage medium

Disclosed are derivatives of protoberberine biological alkaloids or physiologically acceptable salts thereof produced by means of a derivative reaction of a source material of biological alkaline quaternary ammonium salts of protoberberine alkaloids, a preparation method for same and pharmaceutical uses thereof. The derivatives of protoberberine biological alkaloids or the physiologically acceptable salts thereof show activity inhibiting ulcerative colitis and can be used in the preparation of drugs for same. 

Derivatives of protoberberine biological alkaloids and use of same inhibiting ulcerative colitis

Growing community of inventors

Beijing, China

Zhihong Li