Ethicon, Gmbh

Johnson and Johnson Vision Care, Inc.

Johnson & Johnson Gmbh

Depuy Mitek, Inc.

Cordis Neurovascular, Inc.

Zhigang Li

Yufu Li

Kevin L Cooper

Joseph Henry Contiliano

Aruna Nathan

Michael J Trezza, Ii

Qiang Zhang

Raymond S Shissias

Murty Narayan Vyakarnam

Han Cui

Maureen J Borgia

Juan A Lorenzo

Nathan Stewart Cauldwell

Edgar V Menezes

Walter R Laredo

Angelo G Scopelianos

Yue Zhou

Mark B Roller

Hassan Chaouk

Ronald W Marsh

Richard Champion Davis, Iii

Kevor Shane TenHuisen

Bret A Coldren

Jenny J Yuan

David A Dalessandro

Michael J Ii Trezza

The present invention provides a fixation device that includes an elongate shank defining a longitudinal axis and having at least one engaging member for applying the fixation device within tissue and securing the fixation device in the tissue once implanted formed thereon, and a drive head having a proximal end, a distal end and a radial cross-sectional geometry, where the drive head is mated to the elongate shank, and includes at least one anti-rotational member integral therewith, Fixation device kits utilizing the fixation device, and methods of fixation in tissue are also provided.

Medical fixation devices with improved torsional drive head

The invention provides punctal plugs for the delivery of active agent to one or both of the tear fluid of the eye and to the nasolacrimal duct that comprise a body, at least one cap, and optionally a collarette.

Punctal plugs for the delivery of active agents

The invention provides punctal plugs for the delivery of active agent to one or both of the tear fluid of the eye and to the nasolacrimal duct. The plugs of the invention have a body, a reservoir contained within the body, and optionally a collarette. The reservoir has at least one opening and contains a polymeric material and at least one active agent.

A composite having a poly(ethylene-co-acrylic acid) coupling agent, a filler, and a biocompatible, biodegradable polymer matrix is disclosed. The composites are useful for biomedical applications such as, tissue engineering, drug delivery, and implantable medical devices.

Use of coupling agents to improve the interface in absorbable polymer composites

The invention provides devices useful for the delivery of active agents to the eye in a controlled manner. In the devices of the invention, the active agent is present within the device in a continuous or discontinuous concentration gradient.

Ophthalmic devices for the controlled release of active agents

The present invention provides a suture anchor that includes an elongate shank defining a longitudinal axis and having at least one engaging member for applying the suture anchor within the bone and securing the suture anchor in the bone once implanted formed thereon, and a drive head having a proximal end, a distal end and a radial cross-sectional geometry, where the drive head is mated to the elongate shank, includes at least one suture attachment element formed in a portion thereof and at least one anti-rotational member integral therewith, suture anchor kits utilizing the suture anchors and methods of attaching bone to gone.

Suture anchor with improved torsional drive head

A device for use in tissue repair, a method of using the device in a surgical procedure and a method of making the device. The device is an assembly of a cannulated anchor with a cord passed through it, and a stopper to prevent the cord from passing back through the anchor.

Tissue repair device and fabrication thereof

The present invention provides a fixation device that includes an elongate shank defining a longitudinal axis and having at least one engaging member for applying the fixation device within tissue and securing the fixation device in the tissue once implanted formed thereon, and a drive head having a proximal end, a distal end and a radial cross-sectional geometry, where the drive head is mated to the elongate shank, and includes at least one anti-rotational member integral therewith. Fixation device kits utilizing the fixation device, and methods of fixation in tissue are also provided.

A device for use in tissue repair procedures, a surgical tissue repair procedure, and a method of making the device. Specifically, the device is an assembly of a cannulated anchor member with a cord passed through it, and a stopper mounted to an end of the cord to prevent the cord from passing back through the anchor member.

A device for use in tissue repair, a method of using the device in a surgical procedure and a method of making the device. The device is an assembly of a anchor with a cord passed through it, and a stopper to prevent the cord from passing back through the anchor.

A polymeric coating is applied to at least one embolic coil carried in a fixture, at least a portion of said embolic coil being generally vertical and straight. The coil is carried in the fixture during the processing, and may remain in the fixture if desired for further steps of processing.

Method of making active embolic coil

A cutting device for trimming a coiled strand, such as an arterial, urinary or other intraluminal stent made from metal or plastic wire, has a pair of articulating arms connected at a pivot joint. One of the arms has a holding jaw for holding the coiled strand. A second of the arms has a jaw with a cutter. The holding jaw has a passageway through which the coiled strand may be threaded to aid in holding the coiled strand for cutting by the cutter. The holding jaw preferably has a guide channel formed by a pair of tapered walls that slide between adjacent turns of the coiled strand. In accordance with a method of the invention, an end of the coiled strand is introduced through the passageway in the holding jaw. The coiled strand is rotated to advance the coiled strand through the passageway until the coiled strand is positioned beneath the cutting jaw at the selected location. The lever portions and the jaw portions are then urged together, cutting the coiled strand at the selected location.

Trimmer for cutting a coiled strand

The present invention is directed to reinforced, biocompatible, biodegradable compositions suitable for use in implantable medical devices and medical devices made at least in part from such compositions, where the compositions include a biocompatible, biodegradable polymer; a biocompatible, biodegradable wax; and greater than about 30 weight percent of an inorganic filler material.

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Hillsborough, NJ, United States of America

Zhigang Li