Cam Med Ltd.

Massachusetts Institute of Technology

Insulet Corporation

Zhifei Ge

Yanzhe Qin

John R Bussiere

Cullen Richard Buie

Jeffrey Lawrence Moran

Eduardo Luis Latouche

Paulo Andres Garcia Dominguez

John Richard Bussiere

In some embodiments, electrochemical actuators include a sealed electrolytic chamber with two or more electrodes disposed therein and associated reservoirs. In some embodiments, the electrochemical actuators include one or more rigid structures that are overmolded onto one or more electrodes to form the electrolytic chambers. In some embodiments, multiple rigid structures that are overmolded onto two separate electrodes may be connected to form one or more electrolytic chambers with a desired configuration of electrodes contained therein. In some embodiments, manufacturing methods and structures relate to the formation of an array of electrochemical actuators.

Electrochemical actuators and actuator arrays

An electroporation device with a volume of varying cross sectional area that as a fast assay device for determining the optimal conditions for plasma membrane electroporation.

Microfluidic assay for rapid optimization of cell electroporation

A flexible patch pump for controllable accurate subcutaneous delivery of one or more medicaments to a patient includes a laminated layered structure. The pump may have a rigid reservoir layer including a number of rigid reservoirs disposed in a flexible material; a flexible microfluidic layer including a compliant membrane for sealing the rigid reservoirs, a network of microfluidic channels connecting the rigid reservoirs, and a number of inlet and/or outlet valves corresponding to the rigid reservoirs; and a flexible-rigid electronic circuit layer including a number of individually-addressable actuators. In operation, the rigid reservoirs may contain medicament that is dispensed in precise volumes at appropriate times due, for example, to a pressure change in an addressed reservoir caused by displacement of the compliant membrane or other actuation element.

Conformable patch pump

Growing community of inventors

Cambridge, MA, United States of America

Zhifei Ge